Signal transducer and activator of transcription (STAT) 1 and STAT3 are expressed in the human ovary and have Janus kinase 1-independent functions in the COV434 human granulosa cell line.

Frost, E R; Ford, E A; Peters, A E; Reed, N L; McLaughlin, E A; Baker, M A; Lovell-Badge, R; Sutherland, J M

Frost, E R; Ford, E A; Peters, A E; Reed, N L; McLaughlin, E A; Baker, M A; Lovell-Badge, R; Sutherland, J M.

Afiliação

Frost ER; Priority Research Centre for Reproductive Science, Schools of Biomedical Science and Pharmacy and Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; and Hunter Medical Research Institute, Kookaburra Circuit, New Lambton Heights, NSW 2305, Aust
Ford EA; Priority Research Centre for Reproductive Science, Schools of Biomedical Science and Pharmacy and Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; and Hunter Medical Research Institute, Kookaburra Circuit, New Lambton Heights, NSW 2305, Aust
Peters AE; Priority Research Centre for Reproductive Science, Schools of Biomedical Science and Pharmacy and Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; and Hunter Medical Research Institute, Kookaburra Circuit, New Lambton Heights, NSW 2305, Aust
Reed NL; Priority Research Centre for Reproductive Science, Schools of Biomedical Science and Pharmacy and Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia.
McLaughlin EA; Priority Research Centre for Reproductive Science, Schools of Biomedical Science and Pharmacy and Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; and School of Science, Western Sydney University, Penrith, NSW 2751, Australia; and School of
Baker MA; Priority Research Centre for Reproductive Science, Schools of Biomedical Science and Pharmacy and Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; and Hunter Medical Research Institute, Kookaburra Circuit, New Lambton Heights, NSW 2305, Aust
Lovell-Badge R; Stem Cell Biology and Developmental Genetics Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Sutherland JM; Priority Research Centre for Reproductive Science, Schools of Biomedical Science and Pharmacy and Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, NSW 2308, Australia; and Hunter Medical Research Institute, Kookaburra Circuit, New Lambton Heights, NSW 2305, Aust

Reprod Fertil Dev ; 32(12): 1027-1039, 2020 Aug.

Article em En | MEDLINE | ID: mdl-32758351

Assuntos

Células da Granulosa/metabolismo; Janus Quinase 1/metabolismo; Ovário/metabolismo; Fator de Transcrição STAT1/metabolismo; Fator de Transcrição STAT3/metabolismo; Adulto; Linhagem Celular; Inibidores Enzimáticos/farmacologia; Feminino; Células da Granulosa/efeitos dos fármacos; Humanos; Janus Quinase 1/antagonistas & inibidores; Nitrilas; Folículo Ovariano/efeitos dos fármacos; Folículo Ovariano/metabolismo; Pirazóis/farmacologia; Pirimidinas; Fator de Transcrição STAT1/genética; Fator de Transcrição STAT3/genética; Transdução de Sinais/efeitos dos fármacos; Transdução de Sinais/fisiologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ovário / Fator de Transcrição STAT1 / Fator de Transcrição STAT3 / Janus Quinase 1 / Células da Granulosa Limite: Adult / Female / Humans Idioma: En Revista: Reprod Fertil Dev Assunto da revista: MEDICINA REPRODUTIVA Ano de publicação: 2020 Tipo de documento: Article

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