NOX2 decoy peptides disrupt trauma-mediated neutrophil immunosuppression and protect against lethal peritonitis.

Husain, Maroof; Becker, Eugene J; Bone, Nathaniel B; Schmitt, Amy; Pittet, Jean-Francois; Zmijewski, Jaroslaw W

Husain, Maroof; Becker, Eugene J; Bone, Nathaniel B; Schmitt, Amy; Pittet, Jean-Francois; Zmijewski, Jaroslaw W.

Afiliação

Husain M; Department of Medicine, Birmingham, AL, 35294-0012, USA.
Becker EJ; Department of Medicine, Birmingham, AL, 35294-0012, USA.
Bone NB; Department of Medicine, Birmingham, AL, 35294-0012, USA.
Schmitt A; Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294-0012, USA.
Pittet JF; Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294-0012, USA.
Zmijewski JW; Department of Medicine, Birmingham, AL, 35294-0012, USA. Electronic address: zmijewsk@uab.edu.

Redox Biol ; 36: 101651, 2020 09.

Article em En | MEDLINE | ID: mdl-32771683

Assuntos

Neutrófilos; Peritonite; Animais; Humanos; Terapia de Imunossupressão; Camundongos; NADPH Oxidase 2/genética; NADPH Oxidases/genética; Peptídeos

Palavras-chave

HMGB1; NADPH oxidase; Shock

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peritonite / Neutrófilos Limite: Animals / Humans Idioma: En Revista: Redox Biol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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