Precision design of stable genetic circuits carried in highly-insulated E. coli genomic landing pads.

Park, Yongjin; Espah Borujeni, Amin; Gorochowski, Thomas E; Shin, Jonghyeon; Voigt, Christopher A

Precision design of stable genetic circuits carried in highly-insulated E. coli genomic landing pads.

Park, Yongjin; Espah Borujeni, Amin; Gorochowski, Thomas E; Shin, Jonghyeon; Voigt, Christopher A.

Afiliação

Park Y; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Espah Borujeni A; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Gorochowski TE; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Shin J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Voigt CA; Synthetic Biology Center, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Mol Syst Biol ; 16(8): e9584, 2020 08.

Article em En | MEDLINE | ID: mdl-32812710

Assuntos

Escherichia coli/genética; Redes Reguladoras de Genes; Engenharia Genética/métodos; RNA Polimerases Dirigidas por DNA/metabolismo; Proteínas de Escherichia coli/genética; Plasmídeos/genética; Software; Biologia Sintética

Palavras-chave

gene regulatory network; genetic circuit design automation; genome editing; synthetic biology; systems biology

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Engenharia Genética / Escherichia coli / Redes Reguladoras de Genes Idioma: En Revista: Mol Syst Biol Assunto da revista: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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