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Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds.
Caesar, Lindsay K; Robey, Matthew T; Swyers, Michael; Islam, Md N; Ye, Rosa; Vagadia, Purav P; Schiltz, Gary E; Thomas, Paul M; Wu, Chengcang C; Kelleher, Neil L; Keller, Nancy P; Bok, Jin Woo.
Afiliação
  • Caesar LK; Department of Chemistry, Northwestern University, Evanston, Illinois, USA.
  • Robey MT; Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, USA.
  • Swyers M; Intact Genomics, Inc., St. Louis, Missouri, USA.
  • Islam MN; Intact Genomics, Inc., St. Louis, Missouri, USA.
  • Ye R; Intact Genomics, Inc., St. Louis, Missouri, USA.
  • Vagadia PP; Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, Illinois, USA.
  • Schiltz GE; Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, Illinois, USA.
  • Thomas PM; Department of Pharmacology, Northwestern University, Chicago, Illinois, USA.
  • Wu CC; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Kelleher NL; Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, USA.
  • Keller NP; Proteomics Center of Excellence, Northwestern University, Evanston, Illinois, USA.
  • Bok JW; Intact Genomics, Inc., St. Louis, Missouri, USA cwu@intactgenomics.com n-kelleher@northwestern.edu npkeller@wisc.edu jbok@wisc.edu.
mBio ; 11(4)2020 08 25.
Article em En | MEDLINE | ID: mdl-32843555
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aspergillus / Produtos Biológicos / Família Multigênica / Vias Biossintéticas Idioma: En Revista: MBio Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aspergillus / Produtos Biológicos / Família Multigênica / Vias Biossintéticas Idioma: En Revista: MBio Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos