Avobenzone incorporation in a diverse range of Ru(II) scaffolds produces potent potential antineoplastic agents.
Dalton Trans
; 49(35): 12161-12167, 2020 Sep 15.
Article
em En
| MEDLINE
| ID: mdl-32845256
ABSTRACT
Four structurally distinct classes of polypyridyl ruthenium complexes containing avobenzone exhibited low micromolar and submicromolar potencies in cancer cells, and were up to 273-fold more active than the parent ligand. Visible light irradiation enhanced the cytotoxicity of some complexes, making them promising candidates for combined chemo-photodynamic therapy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Propiofenonas
/
Rutênio
/
Complexos de Coordenação
/
Antineoplásicos
Limite:
Humans
Idioma:
En
Revista:
Dalton Trans
Assunto da revista:
QUIMICA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Estados Unidos