Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer.
Chem Commun (Camb)
; 56(77): 11489-11492, 2020 Sep 29.
Article
em En
| MEDLINE
| ID: mdl-32857074
ABSTRACT
Novel thiocarbonyl derivatives (NIS and CRNS) with excellent ROS generation abilities are synthesized and studied as potential photosensitizers for one- and two-photon excited photodynamic therapy. In particular, NIS-Me and CRNS display outstanding phototoxicity toward HeLa cells under two-photon excitation (800 nm) with negligible dark toxicity.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fotoquimioterapia
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Compostos de Sulfidrila
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Desenho de Fármacos
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Fármacos Fotossensibilizantes
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Antineoplásicos
Limite:
Humans
Idioma:
En
Revista:
Chem Commun (Camb)
Assunto da revista:
QUIMICA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Vietnã