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Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.
Sarott, Roman C; Westphal, Matthias V; Pfaff, Patrick; Korn, Claudia; Sykes, David A; Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Weise, Marie; Mostinski, Yelena; Hompluem, Pattarin; Koers, Eline; Miljus, Tamara; Roth, Nicolas J; Asmelash, Hermon; Vong, Man C; Piovesan, Jacopo; Guba, Wolfgang; Rufer, Arne C; Kusznir, Eric A; Huber, Sylwia; Raposo, Catarina; Zirwes, Elisabeth A; Osterwald, Anja; Pavlovic, Anto; Moes, Svenja; Beck, Jennifer; Benito-Cuesta, Irene; Grande, Teresa; Ruiz de Marti N Esteban, Samuel; Yeliseev, Alexei; Drawnel, Faye; Widmer, Gabriella; Holzer, Daniela; van der Wel, Tom; Mandhair, Harpreet; Yuan, Cheng-Yin; Drobyski, William R; Saroz, Yurii; Grimsey, Natasha; Honer, Michael; Fingerle, Jürgen; Gawrisch, Klaus; Romero, Julian; Hillard, Cecilia J; Varga, Zoltan V; van der Stelt, Mario; Pacher, Pal; Gertsch, Jürg; McCormick, Peter J.
Afiliação
  • Sarott RC; Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule Zürich, Vladimir-Prelog-Weg 3, 8093 Zürich, Switzerland.
  • Westphal MV; Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule Zürich, Vladimir-Prelog-Weg 3, 8093 Zürich, Switzerland.
  • Pfaff P; Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule Zürich, Vladimir-Prelog-Weg 3, 8093 Zürich, Switzerland.
  • Korn C; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Sykes DA; Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham NG7 2UH, U.K.
  • Gazzi T; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands B15 2TT, U.K.
  • Brennecke B; Leibniz-Institut für Molekulare Pharmakologie FMP, Campus Berlin-Buch, 13125 Berlin, Germany.
  • Atz K; Leibniz-Institut für Molekulare Pharmakologie FMP, Campus Berlin-Buch, 13125 Berlin, Germany.
  • Weise M; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Mostinski Y; Leibniz-Institut für Molekulare Pharmakologie FMP, Campus Berlin-Buch, 13125 Berlin, Germany.
  • Hompluem P; Leibniz-Institut für Molekulare Pharmakologie FMP, Campus Berlin-Buch, 13125 Berlin, Germany.
  • Koers E; Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham NG7 2UH, U.K.
  • Miljus T; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands B15 2TT, U.K.
  • Roth NJ; Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham NG7 2UH, U.K.
  • Asmelash H; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands B15 2TT, U.K.
  • Vong MC; Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham NG7 2UH, U.K.
  • Piovesan J; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands B15 2TT, U.K.
  • Guba W; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, England.
  • Rufer AC; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, England.
  • Kusznir EA; Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham NG7 2UH, U.K.
  • Huber S; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands B15 2TT, U.K.
  • Raposo C; Faculty of Medicine & Health Sciences, University of Nottingham, Nottingham NG7 2UH, U.K.
  • Zirwes EA; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands B15 2TT, U.K.
  • Osterwald A; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Pavlovic A; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Moes S; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Beck J; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Benito-Cuesta I; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Grande T; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Ruiz de Marti N Esteban S; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Yeliseev A; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Drawnel F; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Widmer G; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Holzer D; Faculty of Experimental Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223, Madrid, Spain.
  • van der Wel T; Faculty of Experimental Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223, Madrid, Spain.
  • Mandhair H; Faculty of Experimental Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223, Madrid, Spain.
  • Yuan CY; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland 20852, United States.
  • Drobyski WR; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Saroz Y; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Grimsey N; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Honer M; Department of Molecular Physiology, Leiden Institute of Chemistry, Leiden University, 2333 CC, Leiden, The Netherlands.
  • Fingerle J; Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland.
  • Gawrisch K; Department of Microbiology and Immunology, Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.
  • Romero J; Department of Medicine, Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.
  • Hillard CJ; Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, University of Auckland, 1142 Auckland, New Zealand.
  • Varga ZV; Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, University of Auckland, 1142 Auckland, New Zealand.
  • van der Stelt M; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Pacher P; Roche Pharma Research & Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
  • Gertsch J; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland 20852, United States.
  • McCormick PJ; Faculty of Experimental Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, 28223, Madrid, Spain.
J Am Chem Soc ; 142(40): 16953-16964, 2020 10 07.
Article em En | MEDLINE | ID: mdl-32902974
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Microglia / Receptor CB2 de Canabinoide / Doença de Alzheimer / Corantes Fluorescentes Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: J Am Chem Soc Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Microglia / Receptor CB2 de Canabinoide / Doença de Alzheimer / Corantes Fluorescentes Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: J Am Chem Soc Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça