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Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study.
Bloor, Adrian J C; Patel, Amit; Griffin, James E; Gilleece, Maria H; Radia, Rohini; Yeung, David T; Drier, Diana; Larson, Laurie S; Uenishi, Gene I; Hei, Derek; Kelly, Kilian; Slukvin, Igor; Rasko, John E J.
Afiliação
  • Bloor AJC; Haematology & Transplant Unit, The Christie NHS Foundation Trust, Manchester, UK. adrian.bloor@christie.nhs.uk.
  • Patel A; School of Medical Sciences, The University of Manchester, Manchester, UK. adrian.bloor@christie.nhs.uk.
  • Griffin JE; Haematology & Transplant Unit, The Christie NHS Foundation Trust, Manchester, UK.
  • Gilleece MH; Department of Bone Marrow Transplantation, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
  • Radia R; Department of Haematology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Yeung DT; Department of Haematology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
  • Drier D; School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
  • Larson LS; Royal Adelaide Hospital, Adelaide, South Australia, Australia.
  • Uenishi GI; Waisman Biomanufacturing, University of Wisconsin-Madison, Madison, WI, USA.
  • Hei D; Waisman Biomanufacturing, University of Wisconsin-Madison, Madison, WI, USA.
  • Kelly K; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, USA.
  • Slukvin I; BlueRock Therapeutics, Cambridge, MA, USA.
  • Rasko JEJ; Cynata Therapeutics Limited, Carlton, Victoria, Australia.
Nat Med ; 26(11): 1720-1725, 2020 11.
Article em En | MEDLINE | ID: mdl-32929265
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esteroides / Transplante de Células-Tronco Mesenquimais / Células-Tronco Pluripotentes Induzidas / Doença Enxerto-Hospedeiro Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esteroides / Transplante de Células-Tronco Mesenquimais / Células-Tronco Pluripotentes Induzidas / Doença Enxerto-Hospedeiro Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido