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Inhibition of EZH2 (Enhancer of Zeste Homolog 2) Attenuates Neuroinflammation via H3k27me3/SOCS3/TRAF6/NF-κB (Trimethylation of Histone 3 Lysine 27/Suppressor of Cytokine Signaling 3/Tumor Necrosis Factor Receptor Family 6/Nuclear Factor-κB) in a Rat Model of Subarachnoid Hemorrhage.
Luo, Yujie; Fang, Yuanjian; Kang, Ruiqing; Lenahan, Cameron; Gamdzyk, Marcin; Zhang, Zeyu; Okada, Takeshi; Tang, Jiping; Chen, Sheng; Zhang, John H.
Afiliação
  • Luo Y; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China (Y.L., Y.F., Z.Z., S.C.).
  • Fang Y; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China (Y.L., Y.F., Z.Z., S.C.).
  • Kang R; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, CA (R.K., C.L., M.G., T.O., J.T., J.H.Z.).
  • Lenahan C; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, CA (R.K., C.L., M.G., T.O., J.T., J.H.Z.).
  • Gamdzyk M; Burrell College of Osteopathic Medicine, Las Cruces, NM (C.L.).
  • Zhang Z; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, CA (R.K., C.L., M.G., T.O., J.T., J.H.Z.).
  • Okada T; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China (Y.L., Y.F., Z.Z., S.C.).
  • Tang J; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China (Y.L., Y.F., Z.Z., S.C.).
  • Chen S; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, CA (R.K., C.L., M.G., T.O., J.T., J.H.Z.).
  • Zhang JH; Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China (Y.L., Y.F., Z.Z., S.C.).
Stroke ; 51(11): 3320-3331, 2020 11.
Article em En | MEDLINE | ID: mdl-32933418
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemorragia Subaracnóidea / Encéfalo / Histonas / NF-kappa B / Fator 6 Associado a Receptor de TNF / Proteína Potenciadora do Homólogo 2 de Zeste / Proteína 3 Supressora da Sinalização de Citocinas / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Stroke Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemorragia Subaracnóidea / Encéfalo / Histonas / NF-kappa B / Fator 6 Associado a Receptor de TNF / Proteína Potenciadora do Homólogo 2 de Zeste / Proteína 3 Supressora da Sinalização de Citocinas / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Stroke Ano de publicação: 2020 Tipo de documento: Article