Telomerase reverse transcriptase downregulation by RNA interference modulates endoplasmic reticulum stress and mitochondrial energy production.

Mohd Zain, Muhammad Zuhair; Ismail, Nor Hayati; Ahmad, Nadhirah; Sulong, Sarina; Karsani, Saiful Anuar; Abdul Majid, Nazia

Mohd Zain, Muhammad Zuhair; Ismail, Nor Hayati; Ahmad, Nadhirah; Sulong, Sarina; Karsani, Saiful Anuar; Abdul Majid, Nazia.

Afiliação

Mohd Zain MZ; Institute of Biological Sciences, Faculty of Science, University Malaya, 50603, Kuala Lumpur, Malaysia.
Ismail NH; Institute of Biological Sciences, Faculty of Science, University Malaya, 50603, Kuala Lumpur, Malaysia.
Ahmad N; Makmal Kesihatan Awam Kebangsaan (National Public Health Laboratory), Ministry of Health, Lot 1853, Kampung Melayu, 47000, Sungai Buloh, Selangor, Malaysia.
Sulong S; Institute of Biological Sciences, Faculty of Science, University Malaya, 50603, Kuala Lumpur, Malaysia.
Karsani SA; Human Genome Center, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150, Kubang Kerian, Kelantan, Malaysia.
Abdul Majid N; Institute of Biological Sciences, Faculty of Science, University Malaya, 50603, Kuala Lumpur, Malaysia.

Mol Biol Rep ; 47(10): 7735-7743, 2020 Oct.

Article em En | MEDLINE | ID: mdl-32959195

Assuntos

Regulação para Baixo; Estresse do Retículo Endoplasmático; Metabolismo Energético; Mitocôndrias/metabolismo; Interferência de RNA; Telomerase/biossíntese; Células HeLa; Humanos; Telomerase/genética

Palavras-chave

ER stress; Mitochondria; Proteomic; TERT; siRNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação para Baixo / Telomerase / Interferência de RNA / Metabolismo Energético / Estresse do Retículo Endoplasmático / Mitocôndrias Limite: Humans Idioma: En Revista: Mol Biol Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Malásia

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