Dysregulated Phosphorylation of p53, Autophagy and Stemness Attributes the Mutant p53 Harboring Colon Cancer Cells Impaired Sensitivity to Oxaliplatin.

Therachiyil, Lubna; Haroon, Javeria; Sahir, Fairooz; Siveen, Kodappully S; Uddin, Shahab; Kulinski, Michal; Buddenkotte, Joerg; Steinhoff, Martin; Krishnankutty, Roopesh

Therachiyil, Lubna; Haroon, Javeria; Sahir, Fairooz; Siveen, Kodappully S; Uddin, Shahab; Kulinski, Michal; Buddenkotte, Joerg; Steinhoff, Martin; Krishnankutty, Roopesh.

Afiliação

Therachiyil L; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Haroon J; Department of Pharmaceutical Sciences, College of Pharmacy, Qatar University, Doha, Qatar.
Sahir F; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Siveen KS; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Uddin S; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Kulinski M; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Buddenkotte J; Department of Dermatology and Venereology, Hamad Medical Corporation, Doha, Qatar.
Steinhoff M; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.
Krishnankutty R; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.

Front Oncol ; 10: 1744, 2020.

Article em En | MEDLINE | ID: mdl-32984059

Palavras-chave

HCT 116; HT 29; autophagy; colon cancer; drug resistance; oxaliplatin; p53; therapy

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Front Oncol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Qatar

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