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Comparison of Rapid to Standard Volumetric Modulated Arc Therapy for Palliative Radiotherapy in Lung Cancer Patients.
Mak, David Y; Fraser, Ian; Ferris, Robynn; James, Kerry; Liu, Mitchell; Thomas, Steven D; McKenzie, Michael; Lefresne, Shilo.
Afiliação
  • Mak DY; Medicine, University of British Columbia, Vancouver, CAN.
  • Fraser I; Radiation Oncology, British Columbia Cancer Agency, Vancouver, CAN.
  • Ferris R; Radiation Oncology, British Columbia Cancer Agency, Vancouver, CAN.
  • James K; Radiation Oncology, British Columbia Cancer Agency, Vancouver, CAN.
  • Liu M; Radiation Oncology, British Columbia Cancer Agency, Vancouver, CAN.
  • Thomas SD; Medical Physics, British Columbia Cancer Agency, Vancouver, CAN.
  • McKenzie M; Radiation Oncology, British Columbia Cancer Agency, Vancouver, CAN.
  • Lefresne S; Radiation Oncology, British Columbia Cancer Agency, Vancouver, CAN.
Cureus ; 12(8): e10055, 2020 Aug 26.
Article em En | MEDLINE | ID: mdl-32999778
ABSTRACT
Patients with incurable lung cancer often present with debilitating symptoms that require urgent palliative radiotherapy. Volumetric modulated arc therapy (VMAT) provides several dosimetric advantages compared to basic non-conformal techniques, but involves complex planning resulting in a slower turn-around time for treatment. A simplified planning technique known as 'rapid VMAT' was developed with an aim to deliver palliative treatment to patients within 48 hours. The purpose of this study was to prospectively compare the dosimetric quality of rapid VMAT plans to standard VMAT plans. Fourteen consecutive rapid VMAT cases were re-planned de novo as per standard VMAT planning guidelines. Planning target volume (PTV) and organs at risk (OARs) were then compared. PTV coverage and dose to OARs including the spinal canal, lung, heart, and esophagus were similar between rapid and standard VMAT. Each plan was ready for treatment within 48 hours of the CT simulation. This study describes an expedited process for which palliative radiotherapy can be delivered to lung tumors with a similar robust quality that is provided for curative intent VMAT radiotherapy plans.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Cureus Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Cureus Ano de publicação: 2020 Tipo de documento: Article