Case report: Candida krusei spondylitis in an immunocompromised patient.
BMC Infect Dis
; 20(1): 739, 2020 Oct 08.
Article
em En
| MEDLINE
| ID: mdl-33032533
ABSTRACT
BACKGROUND:
Invasive infections with Candida krusei are uncommon and rarely complicated by spondylitis. Previous described cases were solely treated with antimycotic therapy, despite guidelines recommending surgical interventions. CASE PRESENTATION We describe a case of C. krusei spondylitis in a patient treated with chemotherapy for acute myeloid leukemia. After induction chemotherapy, the patient developed a candidemia, which was treated with micafungin. One month after the candidemia, the patient was admitted with severe lumbar pain. Spondylitis of the L4 and L5 vertebra was diagnosed on MR-imaging, with signs suggesting an atypical infection. The patient was treated with anidulafungin combined with voriconazole. Despite maximal conservative management symptoms gradually worsened eventually requiring surgical intervention.CONCLUSIONS:
In contrast to previous case reports, antimycotic treatment alone could be insufficient in treating C. krusei spondylitis.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Espondilite
/
Candida
/
Candidíase
/
Hospedeiro Imunocomprometido
Tipo de estudo:
Guideline
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
BMC Infect Dis
Assunto da revista:
DOENCAS TRANSMISSIVEIS
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Holanda