F cell numbers are associated with an X-linked genetic polymorphism and correlate with haematological parameters in patients with sickle cell disease.

Urio, Florence; Nkya, Siana; Rooks, Helen; Mgaya, Josephine A; Masamu, Upendo; Zozimus Sangeda, Raphael; Mmbando, Bruno P; Brumat, Marco; Mselle, Ted; Menzel, Stephan; Luzzatto, Lucio; Makani, Julie

Urio, Florence; Nkya, Siana; Rooks, Helen; Mgaya, Josephine A; Masamu, Upendo; Zozimus Sangeda, Raphael; Mmbando, Bruno P; Brumat, Marco; Mselle, Ted; Menzel, Stephan; Luzzatto, Lucio; Makani, Julie.

Afiliação

Urio F; Muhimbili Sickle Cell Programme, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Nkya S; Department of Biochemistry, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Rooks H; Muhimbili Sickle Cell Programme, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Mgaya JA; Department of Biological Sciences, Dar es salaam University College of Education, University of Dar es Salaam, Dar es Salaam, Tanzania.
Masamu U; Comprehensive Cancer Centre, Kings College London, London, UK.
Zozimus Sangeda R; Muhimbili Sickle Cell Programme, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Mmbando BP; Muhimbili Sickle Cell Programme, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Brumat M; Muhimbili Sickle Cell Programme, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Mselle T; Department of Pharmaceutical Microbiology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Menzel S; Muhimbili Sickle Cell Programme, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Luzzatto L; National Institute for Medical Research, Tanga, Tanzania.
Makani J; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.

Br J Haematol ; 191(5): 888-896, 2020 12.

Article em En | MEDLINE | ID: mdl-33073380

Assuntos

Anemia Falciforme; Cromossomos Humanos X/genética; Eritrócitos Anormais/metabolismo; Genes Ligados ao Cromossomo X; Polimorfismo Genético; Proteínas Repressoras/genética; Reticulócitos/metabolismo; Adolescente; Adulto; Anemia Falciforme/sangue; Anemia Falciforme/genética; Criança; Pré-Escolar; Feminino; Humanos; Masculino; Pessoa de Meia-Idade

Palavras-chave

F cells; genetic variants; haematological parameters; sickle cell disease

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Proteínas Repressoras / Reticulócitos / Cromossomos Humanos X / Eritrócitos Anormais / Genes Ligados ao Cromossomo X / Anemia Falciforme Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: En Revista: Br J Haematol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Tanzânia

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