Next-generation sequencing reveals alternative L-DOPA decarboxylase (DDC) splice variants bearing novel exons, in human hepatocellular and lung cancer cells.

Papatsirou, Maria; Adamopoulos, Panagiotis G; Artemaki, Pinelopi I; Georganti, Vasiliki P; Scorilas, Andreas; Vassilacopoulou, Dido; Kontos, Christos K

Papatsirou, Maria; Adamopoulos, Panagiotis G; Artemaki, Pinelopi I; Georganti, Vasiliki P; Scorilas, Andreas; Vassilacopoulou, Dido; Kontos, Christos K.

Afiliação

Papatsirou M; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
Adamopoulos PG; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
Artemaki PI; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
Georganti VP; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
Scorilas A; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece.
Vassilacopoulou D; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: didovass@biol.uoa.gr.
Kontos CK; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: chkontos@biol.uoa.gr.

Gene ; 768: 145262, 2021 Feb 05.

Article em En | MEDLINE | ID: mdl-33141052

Assuntos

Descarboxilases de Aminoácido-L-Aromático/genética; Carcinoma Hepatocelular/genética; Dopa Descarboxilase/genética; Neoplasias Hepáticas/genética; Neoplasias Pulmonares/genética; Algoritmos; Processamento Alternativo/genética; Linhagem Celular Tumoral; Predisposição Genética para Doença/genética; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; Fases de Leitura Aberta/genética; Isoformas de Proteínas/genética

Palavras-chave

Alternative splicing; Aromatic L-amino acid decarboxylase (AADC); High-throughput sequencing; Liver carcinoma; Lung adenocarcinoma; Transcriptional analysis

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Descarboxilases de Aminoácido-L-Aromático / Carcinoma Hepatocelular / Dopa Descarboxilase / Neoplasias Hepáticas / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Gene Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Grécia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google