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The future of Extracellular Vesicles as Theranostics - an ISEV meeting report.
Soekmadji, Carolina; Li, Bo; Huang, Yiyao; Wang, Haifang; An, Taixue; Liu, Chunchen; Pan, Weilun; Chen, Jing; Cheung, Lesley; Falcon-Perez, Juan Manuel; Gho, Yong Song; Holthofer, Harry B; Le, Minh T N; Marcilla, Antonio; O'Driscoll, Lorraine; Shekari, Faezeh; Shen, Tang Long; Torrecilhas, Ana Claudia; Yan, Xiaomei; Yang, Fuquan; Yin, Hang; Xiao, Yu; Zhao, Zezhou; Zou, Xue; Wang, Qian; Zheng, Lei.
Afiliação
  • Soekmadji C; Department of Cell and Molecular Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Li B; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
  • Huang Y; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Wang H; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • An T; Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Liu C; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Pan W; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Chen J; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Cheung L; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Falcon-Perez JM; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Gho YS; The Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.
  • Holthofer HB; Exosomes Laboratory and Metabolomics Platform, Center for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain.
  • Le MTN; Centro De Investigación Biomédica En Red De Enfermedades Hepáticas Y Digestivas (Ciberehd), Madrid, Spain.
  • Marcilla A; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.
  • O'Driscoll L; Laboratory of Intercellular Communication, Department of Life Science, POSTECH, South Korea.
  • Shekari F; Medical Department, University Medical Center Hamburg-Eppendorf, Germany.
  • Shen TL; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Torrecilhas AC; Àrea De Parasitologia, Departament De Farmàcia I Tecnologia Farmacèutica I Parasitologia, Universitat De València, Burjassot, Valencia, Spain.
  • Yan X; Joint Research Unit on Endocrinology, Nutrition and Clinical Dietetics, Health Research Institute La Fe-Universitat De Valencia, Valencia, Spain.
  • Yang F; School of Pharmacy and Pharmaceutical Sciences, Panoz Institute & Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
  • Yin H; Trinity St. James's Cancer Institute (TSJCI), Trinity College Dublin, Dublin, Ireland.
  • Xiao Y; Department of Stem Cells and Developmental BiologyCell Science, Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
  • Zhao Z; Department of Plant Pathology and Microbiology & Center for Biotechnology, National Taiwan University, Taipei, Taiwan.
  • Zou X; Departamento De Ciências Farmacêuticas, UNIFESP, Diadema, São Paulo, Brazil.
  • Wang Q; Department of Chemical Biology, the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, the Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian, China.
  • Zheng L; Laboratory of Proteomics, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
J Extracell Vesicles ; 9(1): 1809766, 2020 Sep 04.
Article em En | MEDLINE | ID: mdl-33144926
ABSTRACT
The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on "EVs in Clinical Theranostic". Here, we report the conclusions of roundtable discussions on the current advancement in the analysis technologies and we provide some guidelines to researchers in the field to consider the use of EVs in clinical application. The main challenges and the requirements for EV separation and characterization strategies, quality control and clinical investigation were discussed to promote the application of EVs in future clinical studies.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Qualitative_research Idioma: En Revista: J Extracell Vesicles Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Qualitative_research Idioma: En Revista: J Extracell Vesicles Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Austrália