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Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes.
Schuldt, Maike; Johnston, Jamie R; He, Huan; Huurman, Roy; Pei, Jiayi; Harakalova, Magdalena; Poggesi, Corrado; Michels, Michelle; Kuster, Diederik W D; Pinto, Jose R; van der Velden, Jolanda.
Afiliação
  • Schuldt M; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands. Electronic address: m.schuldt@amsterdamumc.nl.
  • Johnston JR; Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL, USA.
  • He H; Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL, USA; Institute of Molecular Biophysics, Florida State University, Tallahassee, FL, USA.
  • Huurman R; Department of Cardiology, Thorax Center, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Pei J; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands; Regenerative Medicine Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Harakalova M; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands; Regenerative Medicine Utrecht, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Poggesi C; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Michels M; Department of Cardiology, Thorax Center, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Kuster DWD; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.
  • Pinto JR; Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL, USA.
  • van der Velden J; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Physiology, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.
J Mol Cell Cardiol ; 150: 77-90, 2021 01.
Article em En | MEDLINE | ID: mdl-33148509

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiomiopatia Hipertrófica / Troponina T / Miócitos Cardíacos / Mutação / Miofibrilas Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Mol Cell Cardiol Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cardiomiopatia Hipertrófica / Troponina T / Miócitos Cardíacos / Mutação / Miofibrilas Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Mol Cell Cardiol Ano de publicação: 2021 Tipo de documento: Article