Can eosinophils in adipose tissue add fuel to the fire?
Immunol Cell Biol
; 99(1): 13-16, 2021 01.
Article
em En
| MEDLINE
| ID: mdl-33167058
ABSTRACT
In inguinal adipose tissue, beige adipocytes are interspersed among white adipocytes and in close communication with dynamic populations of immune cells. Recent data have demonstrated that anti-inflammatory macrophages (M2) increase thermogenic activity of beige adipocytes, although the mechanism is currently under debate. ILC2, cells via secretion, of methionine enkephalin peptide were found to be able to increase beige thermogenesis. Knights et al. have recently generated a whole-body knock-out of KLF3 (KLF3-/-) to explore its contribution to thermogenesis and weight gain in a diet-induced obesity animal model.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Eosinófilos
/
Imunidade Inata
Limite:
Animals
Idioma:
En
Revista:
Immunol Cell Biol
Assunto da revista:
ALERGIA E IMUNOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos