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Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial.
Sculier, Delphine; Wandeler, Gilles; Yerly, Sabine; Marinosci, Annalisa; Stoeckle, Marcel; Bernasconi, Enos; Braun, Dominique L; Vernazza, Pietro; Cavassini, Matthias; Buzzi, Marta; Metzner, Karin J; Decosterd, Laurent A; Günthard, Huldrych F; Schmid, Patrick; Limacher, Andreas; Egger, Matthias; Calmy, Alexandra.
Afiliação
  • Sculier D; HIV/AIDS Unit, Department of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
  • Wandeler G; Private Practice Office, Geneva, Switzerland.
  • Yerly S; Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Marinosci A; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
  • Stoeckle M; Laboratory of Virology, Geneva University Hospitals, Geneva, Switzerland.
  • Bernasconi E; HIV/AIDS Unit, Department of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
  • Braun DL; Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, University of Basel, Switzerland.
  • Vernazza P; Service of Infectious Diseases, Lugano Regional Hospital, Lugano, Switzerland.
  • Cavassini M; Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
  • Buzzi M; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
  • Metzner KJ; Division of Infectious Diseases and Hospital Epidemiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Decosterd LA; Department of Infectious Diseases, University Hospital of Lausanne, Lausanne, Switzerland.
  • Günthard HF; HIV/AIDS Unit, Department of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
  • Schmid P; Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
  • Limacher A; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
  • Egger M; Pharmacology Laboratory, Clinical Pharmacology Department, University of Lausanne, Lausanne, Switzerland.
  • Calmy A; Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.
PLoS Med ; 17(11): e1003421, 2020 11.
Article em En | MEDLINE | ID: mdl-33170863

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxazinas / Piperazinas / Piridonas / Infecções por HIV / HIV-1 / Soropositividade para HIV / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials / Guideline Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxazinas / Piperazinas / Piridonas / Infecções por HIV / HIV-1 / Soropositividade para HIV / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials / Guideline Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: PLoS Med Assunto da revista: MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suíça