HDAC6 as privileged target in drug discovery: A perspective.

Pulya, Sravani; Amin, Sk Abdul; Adhikari, Nilanjan; Biswas, Swati; Jha, Tarun; Ghosh, Balaram

Pulya, Sravani; Amin, Sk Abdul; Adhikari, Nilanjan; Biswas, Swati; Jha, Tarun; Ghosh, Balaram.

Afiliação

Pulya S; Epigenetic Research Laboratory, Department of Pharmacy, BITS-Pilani, Hyderabad Campus, Shamirpet, Hyderabad 500078, India.
Amin SA; Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, P. O. Box 17020, Jadavpur University, Kolkata 700032, India.
Adhikari N; Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, P. O. Box 17020, Jadavpur University, Kolkata 700032, India.
Biswas S; Epigenetic Research Laboratory, Department of Pharmacy, BITS-Pilani, Hyderabad Campus, Shamirpet, Hyderabad 500078, India.
Jha T; Natural Science Laboratory, Division of Medicinal and Pharmaceutical Chemistry, Department of Pharmaceutical Technology, P. O. Box 17020, Jadavpur University, Kolkata 700032, India. Electronic address: tjupharm@yahoo.com.
Ghosh B; Epigenetic Research Laboratory, Department of Pharmacy, BITS-Pilani, Hyderabad Campus, Shamirpet, Hyderabad 500078, India. Electronic address: balaram@hyderabad.bits-pilani.ac.in.

Pharmacol Res ; 163: 105274, 2021 01.

Article em En | MEDLINE | ID: mdl-33171304

Assuntos

Descoberta de Drogas; Desacetilase 6 de Histona/metabolismo; Animais; Desacetilase 6 de Histona/química; Humanos; Neoplasias/metabolismo; Doenças Neurodegenerativas/metabolismo

Palavras-chave

Belinostat: (PubChem CID: 6918638); Cancer; Chemical compounds studied in this article; Chidamide: (PubChem CID: 9800555); Citarinostat/ACY-241: (PubChem CID: 53340426); Drug design and discovery; HDAC6; HDAC6 inhibitor; Neurological disease; Panobinostat: (PubChem CID: 6918837); Pracinostat: (PubChem CID: 49855250); Riconilostat/ACY-1215: (PubChem CID: 53340666); Romidepsin: (PubChem CID: 5352062); Structure-activity relationship; Vorinostat: (PubChem CID: 5311)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Descoberta de Drogas / Desacetilase 6 de Histona Limite: Animals / Humans Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Índia

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