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JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome.
Tuttle, Kathryn D; Waugh, Katherine A; Araya, Paula; Minter, Ross; Orlicky, David J; Ludwig, Michael; Andrysik, Zdenek; Burchill, Matthew A; Tamburini, Beth A J; Sempeck, Colin; Smith, Keith; Granrath, Ross; Tracy, Dayna; Baxter, Jessica; Espinosa, Joaquin M; Sullivan, Kelly D.
Afiliação
  • Tuttle KD; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Waugh KA; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Araya P; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Minter R; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Orlicky DJ; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Ludwig M; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Andrysik Z; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Burchill MA; Division of Gastroenterology and Hepatology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Tamburini BAJ; Division of Gastroenterology and Hepatology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Sempeck C; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Smith K; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Granrath R; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Tracy D; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Baxter J; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Espinosa JM; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: joaquin.espinosa@cuanschutz.edu.
  • Sullivan KD; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; Section of Developmental Biology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: kelly.d.sullivan@cuanschutz.edu.
Cell Rep ; 33(7): 108407, 2020 11 17.
Article em En | MEDLINE | ID: mdl-33207208
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Azetidinas / Síndrome de Down / Inibidores de Proteínas Quinases / Janus Quinase 1 / Janus Quinase 2 / Hipersensibilidade Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sulfonamidas / Azetidinas / Síndrome de Down / Inibidores de Proteínas Quinases / Janus Quinase 1 / Janus Quinase 2 / Hipersensibilidade Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos