CO2-based C-arm computed tomography (CACT) of the pelvic arteries: feasibility and diagnostic performance in comparison to CO2-angiography in patients with peripheral arterial disease.
Acta Radiol
; 62(12): 1707-1715, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-33225716
ABSTRACT
BACKGROUND:
Patients with substantially impaired kidney function and peripheral arterial disease (PAD) underwent comparative CO2-based depiction of the pelvic arteries (PAs).PURPOSE:
To evaluate the feasibility and diagnostic performance of CO2-based C-arm computed tomography (CACT) and compare its depiction of PAs with CO2-digital subtraction angiography (DSA). MATERIAL ANDMETHODS:
Fifteen patients (10 men, mean age 70 ± 11 years) with PAD received CO2-DSA and CO2-CACT of the PAs, depicted from the aorta to femoral arteries. These were divided into nine segments (135 in total) and graded by two independent readers for image quality (IQ; 1 = sufficient, 2 = minimal impairments, 3 = insufficient, 4 = outside field of view) and subsequent stenosis grading (SG; grade 1 normal to grade 4 occlusion), under exclusion of all segments with insufficient IQ. Inter-observer and inter-modality agreement calculation and subsequent consensus reading were performed and correlated to a standard of reference (StOR), representing a modality consensus.RESULTS:
Of 135 segments, 117 showed sufficient IQ, excluding 18 segments (10 CACT, 8 DSA). Inter-observer agreement for IQ and consecutive SG demonstrated good to excellent agreement IQDSA κ = 0.83, IQCACT κ = 0.76; StenosisDSA κ = 0.71, StenosisCACT κ = 0.84. Inter-modality agreement for SG lay at κ = 0.76 and κ = 0.65, respectively. More stenoses could be detected by CACT, and analysis of pooled consensus values of SG in CACTcons versus StOR showed an excellent agreement (κ = 0.96) that proved considerably higher than the moderate agreement between consensus values in DSAcons versus StOR (κ = 0.43).CONCLUSION:
CO2-CACT proved feasible, and has the potential to optimize angiographic work-up of PAD in patients with contraindications for other contrast media.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Pelve
/
Artérias
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Dióxido de Carbono
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Tomografia Computadorizada por Raios X
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Angiografia Digital
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Doença Arterial Periférica
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Aged
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Aged80
/
Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Acta Radiol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Alemanha