AAV8 transduction capacity is reduced by prior exposure to endosome-like pH conditions.

Lowell, Jeffrey A; Mah, Kar Men; Bixby, John L; Lemmon, Vance P

Lowell, Jeffrey A; Mah, Kar Men; Bixby, John L; Lemmon, Vance P.

Afiliação

Lowell JA; Miami Project to Cure Paralysis, University of Miami, Miami, FL, USA.
Mah KM; Miami Project to Cure Paralysis, University of Miami, Miami, FL, USA.
Bixby JL; Miami Project to Cure Paralysis; Department of Neurological Surgery; Department of Molecular and Cellular Pharmacology, University of Miami, Miami, FL, USA.
Lemmon VP; Miami Project to Cure Paralysis; Department of Neurological Surgery, University of Miami, Miami, FL, USA.

Neural Regen Res ; 16(5): 851-855, 2021 May.

Article em En | MEDLINE | ID: mdl-33229719

Palavras-chave

adeno-associated virus; autolytic; capsid; low pH; protease; proteolytic; temperature; trafficking; transduction; viral inactivation

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Neural Regen Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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