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Tau and other proteins found in Alzheimer's disease spinal fluid are linked to retromer-mediated endosomal traffic in mice and humans.
Simoes, Sabrina; Neufeld, Jessica L; Triana-Baltzer, Gallen; Moughadam, Setareh; Chen, Emily I; Kothiya, Milankumar; Qureshi, Yasir H; Patel, Vivek; Honig, Lawrence S; Kolb, Hartmuth; Small, Scott A.
Afiliação
  • Simoes S; Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Neufeld JL; Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Triana-Baltzer G; Neuroscience Biomarkers, Janssen Research and Development, San Diego, CA 92121, USA.
  • Moughadam S; Neuroscience Biomarkers, Janssen Research and Development, San Diego, CA 92121, USA.
  • Chen EI; Thermo Fisher Precision Medicine Science Center, 790 Memorial Drive, Cambridge, MA 02139, USA.
  • Kothiya M; Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Qureshi YH; Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Patel V; Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Honig LS; Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Kolb H; Department of Neurology, Columbia University Irving Medical Center, New York, NY 10032, USA.
  • Small SA; Gertrude H. Sergievsky Center, Columbia University Irving Medical Center, New York, NY 10032, USA.
Sci Transl Med ; 12(571)2020 11 25.
Article em En | MEDLINE | ID: mdl-33239387

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos