EPB41 suppresses the Wnt/ß-catenin signaling in non-small cell lung cancer by sponging ALDOC.

Yuan, Jupeng; Xing, Huaixin; Li, Yankang; Song, Yemei; Zhang, Nasha; Xie, Mengyu; Liu, Jiandong; Xu, Yeyang; Shen, Yue; Wang, Bowen; Zhang, Li; Yang, Ming

Yuan, Jupeng; Xing, Huaixin; Li, Yankang; Song, Yemei; Zhang, Nasha; Xie, Mengyu; Liu, Jiandong; Xu, Yeyang; Shen, Yue; Wang, Bowen; Zhang, Li; Yang, Ming.

Afiliação

Yuan J; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China.
Xing H; Department of Anesthesiology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China.
Li Y; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China; Cheeloo College of Medicine, Shandong University, Jinan, Shandong Pro
Song Y; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China.
Zhang N; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China.
Xie M; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China; Cheeloo College of Medicine, Shandong University, Jinan, Shandong Pro
Liu J; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China.
Xu Y; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China; Cheeloo College of Medicine, Shandong University, Jinan, Shandong Pro
Shen Y; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China; Cheeloo College of Medicine, Shandong University, Jinan, Shandong Pro
Wang B; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China; Cheeloo College of Medicine, Shandong University, Jinan, Shandong Pro
Zhang L; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. Electronic address: luzigang@163.com.
Yang M; Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, China; Cheeloo College of Medicine, Shandong University, Jinan, Shandong Pro

Cancer Lett ; 499: 255-264, 2021 02 28.

Article em En | MEDLINE | ID: mdl-33242559

Assuntos

Carcinoma Pulmonar de Células não Pequenas/patologia; Proteínas do Citoesqueleto/metabolismo; Neoplasias Pulmonares/patologia; Proteínas de Membrana/metabolismo; Proteínas Supressoras de Tumor/metabolismo; Animais; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/mortalidade; Carcinoma Pulmonar de Células não Pequenas/cirurgia; Linhagem Celular Tumoral; Núcleo Celular/metabolismo; Citoplasma/metabolismo; Proteínas do Citoesqueleto/genética; Feminino; Regulação Neoplásica da Expressão Gênica; Técnicas de Silenciamento de Genes; Glicogênio Sintase Quinase 3 beta/metabolismo; Humanos; Estimativa de Kaplan-Meier; Pulmão/citologia; Pulmão/patologia; Pulmão/cirurgia; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/mortalidade; Neoplasias Pulmonares/cirurgia; Proteínas de Membrana/genética; Camundongos; Pneumonectomia; Proteólise; RNA Interferente Pequeno/metabolismo; Ativação Transcricional; Proteínas Supressoras de Tumor/genética; Via de Sinalização Wnt; Ensaios Antitumorais Modelo de Xenoenxerto; beta Catenina/metabolismo

Palavras-chave

Aldolase; Erythrocyte membrane protein band 4.1; Fructose-bisphosphate C; NSCLC; Xenograft; ß-Catenin destruction complex

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Proteínas do Citoesqueleto / Proteínas Supressoras de Tumor / Neoplasias Pulmonares / Proteínas de Membrana Tipo de estudo: Observational_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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