The effects of Kctd12, an auxiliary subunit of GABA<sub>B</sub> receptor in dentate gyrus on behavioral response to chronic social defeat stress in mice.

Deng, Si-Long; Hu, Zhuang-Li; Mao, Li; Gao, Bo; Yang, Qiong; Wang, Fang; Chen, Jian-Guo

The effects of Kctd12, an auxiliary subunit of GABA_B receptor in dentate gyrus on behavioral response to chronic social defeat stress in mice.

Deng, Si-Long; Hu, Zhuang-Li; Mao, Li; Gao, Bo; Yang, Qiong; Wang, Fang; Chen, Jian-Guo.

Afiliação

Deng SL; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Hu ZL; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Hubei Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation (HUST), Wuhan, 430030, China; Laboratory of Neuropsychiatric Diseases, The In
Mao L; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Gao B; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Yang Q; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Wang F; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Hubei Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation (HUST), Wuhan, 430030, China; Laboratory of Neuropsychiatric Diseases, The In
Chen JG; Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Hubei Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation (HUST), Wuhan, 430030, China; Laboratory of Neuropsychiatric Diseases, The In

Pharmacol Res ; 163: 105355, 2021 01.

Article em En | MEDLINE | ID: mdl-33285230

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Comportamento Animal; Derrota Social; Estresse Psicológico/metabolismo; Proteínas Adaptadoras de Transdução de Sinal/genética; Animais; Antidepressivos/farmacologia; Giro Denteado/metabolismo; Depressão/metabolismo; Modelos Animais de Doenças; Fluoxetina/farmacologia; Masculino; Camundongos Endogâmicos C57BL; Subunidades Proteicas; RNA Interferente Pequeno/genética; Receptores de GABA-B

Palavras-chave

CGP35348 (CID: 107699); Dentate gyrus; Depression; Fluoxetine; Fluoxetine (CID: 62857); GABA(B)R antagonists; Kctd12; Neuronal excitability

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Comportamento Animal / Proteínas Adaptadoras de Transdução de Sinal / Derrota Social Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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