Quinazolinones as Competitive Inhibitors of Carbonic Anhydrase-II (Human and Bovine): Synthesis, <i>in-vitro, in-silico</i>, Selectivity, and Kinetics Studies.

Khan, Ajmal; Khan, Majid; Halim, Sobia Ahsan; Khan, Zulfiqar Ali; Shafiq, Zahid; Al-Harrasi, Ahmed

Quinazolinones as Competitive Inhibitors of Carbonic Anhydrase-II (Human and Bovine): Synthesis, in-vitro, in-silico, Selectivity, and Kinetics Studies.

Khan, Ajmal; Khan, Majid; Halim, Sobia Ahsan; Khan, Zulfiqar Ali; Shafiq, Zahid; Al-Harrasi, Ahmed.

Afiliação

Khan A; Natural and Medical Sciences Research Center, University of Nizwa, Nizwa, Oman.
Khan M; Natural and Medical Sciences Research Center, University of Nizwa, Nizwa, Oman.
Halim SA; International Center for Chemical and Biological Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan.
Khan ZA; Natural and Medical Sciences Research Center, University of Nizwa, Nizwa, Oman.
Shafiq Z; Department of Chemistry, Government College University, Faisalabad, Pakistan.
Al-Harrasi A; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.

Front Chem ; 8: 598095, 2020.

Article em En | MEDLINE | ID: mdl-33335888

Palavras-chave

bovine carbonic anhydrase-II; human carbonic anhydrase-II; kinetics; molecular docking; quinazolinones; structure-activity relationship

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Front Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Omã

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Front Chem Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Omã