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Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease.
Jamialahmadi, Oveis; Mancina, Rosellina Margherita; Ciociola, Ester; Tavaglione, Federica; Luukkonen, Panu K; Baselli, Guido; Malvestiti, Francesco; Thuillier, Dorothée; Raverdy, Violeta; Männistö, Ville; Pipitone, Rosaria Maria; Pennisi, Grazia; Prati, Daniele; Spagnuolo, Rocco; Petta, Salvatore; Pihlajamäki, Jussi; Pattou, François; Yki-Järvinen, Hannele; Valenti, Luca; Romeo, Stefano.
Afiliação
  • Jamialahmadi O; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden.
  • Mancina RM; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden.
  • Ciociola E; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden.
  • Tavaglione F; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden; Clinical Medicine and Hepatology Unit, Department of Internal Medicine and Geriatrics, Campus Bio-Medico University, Rome, Italy.
  • Luukkonen PK; Department of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland; Department of Internal Medicine, Yale University, New Haven, Connecticut.
  • Baselli G; Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
  • Malvestiti F; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy.
  • Thuillier D; Univ Lille, Inserm, Lille Pasteur Institute, Centre Hospitalier Universitaire de Lille, European Genomic Institute for Diabetes, U1190 Translational Research in Diabetes, Lille University, Lille, France.
  • Raverdy V; Univ Lille, Inserm, Lille Pasteur Institute, Centre Hospitalier Universitaire de Lille, European Genomic Institute for Diabetes, U1190 Translational Research in Diabetes, Lille University, Lille, France; Centre Hospitalier Universitaire de Lille, Department of General and Endocrine Surgery, Integrat
  • Männistö V; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Finland; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Department of Medicine, Endocrinology and Clinical Nutrition, Kuopio University Hospital, Finland.
  • Pipitone RM; Section of Gastroenterology and Hepatology, Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro," University of Palermo, Palermo, Italy.
  • Pennisi G; Section of Gastroenterology and Hepatology, Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro," University of Palermo, Palermo, Italy.
  • Prati D; Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
  • Spagnuolo R; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy.
  • Petta S; Section of Gastroenterology and Hepatology, Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro," University of Palermo, Palermo, Italy.
  • Pihlajamäki J; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Finland; Department of Medicine, Endocrinology and Clinical Nutrition, Kuopio University Hospital, Finland.
  • Pattou F; Univ Lille, Inserm, Lille Pasteur Institute, Centre Hospitalier Universitaire de Lille, European Genomic Institute for Diabetes, U1190 Translational Research in Diabetes, Lille University, Lille, France; Centre Hospitalier Universitaire de Lille, Department of General and Endocrine Surgery, Integrat
  • Yki-Järvinen H; Department of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Minerva Foundation Institute for Medical Research, Helsinki, Finland.
  • Valenti L; Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy. Elect
  • Romeo S; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Gothenburg, Sweden; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy; Cardiology Department, Sah
Gastroenterology ; 160(5): 1634-1646.e7, 2021 04.
Article em En | MEDLINE | ID: mdl-33347879
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apolipoproteínas E / Variação Genética / Alanina Transaminase / 1-Acilglicerol-3-Fosfato O-Aciltransferase / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Gastroenterology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suécia
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Apolipoproteínas E / Variação Genética / Alanina Transaminase / 1-Acilglicerol-3-Fosfato O-Aciltransferase / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Gastroenterology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suécia