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STOPPFall (Screening Tool of Older Persons Prescriptions in older adults with high fall risk): a Delphi study by the EuGMS Task and Finish Group on Fall-Risk-Increasing Drugs.
Seppala, Lotta J; Petrovic, Mirko; Ryg, Jesper; Bahat, Gulistan; Topinkova, Eva; Szczerbinska, Katarzyna; van der Cammen, Tischa J M; Hartikainen, Sirpa; Ilhan, Birkan; Landi, Francesco; Morrissey, Yvonne; Mair, Alpana; Gutiérrez-Valencia, Marta; Emmelot-Vonk, Marielle H; Mora, María Ángeles Caballero; Denkinger, Michael; Crome, Peter; Jackson, Stephen H D; Correa-Pérez, Andrea; Knol, Wilma; Soulis, George; Gudmundsson, Adalsteinn; Ziere, Gijsbertus; Wehling, Martin; O'Mahony, Denis; Cherubini, Antonio; van der Velde, Nathalie.
Afiliação
  • Seppala LJ; Department of Internal Medicine, Section of Geriatric Medicine, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Petrovic M; Department of Internal Medicine and Paediatrics (section of Geriatrics), Ghent University, Ghent, Belgium.
  • Ryg J; Department of Geriatric Medicine, Odense University Hospital, Odense, Denmark and Geriatric Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
  • Bahat G; Istanbul Medical School, Department of Internal Medicine, Division of Geriatrics, Istanbul University, Capa, Istanbul, Turkey.
  • Topinkova E; Department of Geriatrics and Gerontology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic and Faculty of Health and Social Sciences, South Bohemian University, Ceske Budejovice, Czech Republic.
  • Szczerbinska K; Laboratory for Research on Aging Society, Department of Sociology of Medicine, Epidemiology and Preventive Medicine Chair, Faculty of Medicine, Jagiellonian University Medical College, Krakow, Poland.
  • van der Cammen TJM; Faculty of Industrial Design Engineering, Delft University of Technology, Delft, The Netherlands.
  • Hartikainen S; School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
  • Ilhan B; Division of Geriatrics, Department of Internal Medicine, Sisli Hamidiye Etfal Training and Research Hospital, University of Medical Sciences, Istanbul, Turkey.
  • Landi F; Department of Gerontology, Neuroscience and Orthopedics, Catholic University of the Sacred Heart, Rome, Italy.
  • Morrissey Y; Health Care of Older People, East Kent Hospitals University NHS Foundation Trust, Canterbury, Kent, UK.
  • Mair A; Effective Prescribing and Therapeutics, Health and Social Care Directorate, Scottish Government, Edinburgh, Scotland, UK.
  • Gutiérrez-Valencia M; Unit of Innovation and Organization, Navarre Health Service, Pamplona, Spain.
  • Emmelot-Vonk MH; Department of Geriatrics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Mora MÁC; Servicio de Geriatría, Hospital General Universitario de Ciudad Real and CIBER de Fragilidad y Envejecimiento Saludable, Spain.
  • Denkinger M; Agaplesion Bethesda Clinic, Geriatric Research Unit Ulm University and Geriatric Centre Ulm, Ulm, Germany.
  • Crome P; Research Department of Primary Care and Population Health, University College London, London, UK.
  • Jackson SHD; Department of Clinical Gerontology, King's College, London, England, UK.
  • Correa-Pérez A; Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain.
  • Knol W; Department of Geriatric Medicine and Expertise Centre Pharmacotherapy in Old Persons, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Soulis G; Outpatient Geriatric Assessment Unit, Henry Dunant Hospital Center, Athens, Greece.
  • Gudmundsson A; Landspitali University Hospital, Iceland and Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Ziere G; Department of Internal Medicine, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands and Department of Epidemiology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
  • Wehling M; Institute for Clinical Pharmacology, Medical Faculty Mannheim, Ruprecht-Karls-University Heidelberg, Germany.
  • O'Mahony D; Department of Geriatric Medicine, Cork University Hospital, Cork, Ireland and Department of Medicine, University College Cork, Cork, Ireland.
  • Cherubini A; Geriatria, Accettazione Geriatrica e Centro di ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy.
  • van der Velde N; Department of Internal Medicine, Section of Geriatric Medicine, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Age Ageing ; 50(4): 1189-1199, 2021 06 28.
Article em En | MEDLINE | ID: mdl-33349863
ABSTRACT

BACKGROUND:

Healthcare professionals are often reluctant to deprescribe fall-risk-increasing drugs (FRIDs). Lack of knowledge and skills form a significant barrier and furthermore, there is no consensus on which medications are considered as FRIDs despite several systematic reviews. To support clinicians in the management of FRIDs and to facilitate the deprescribing process, STOPPFall (Screening Tool of Older Persons Prescriptions in older adults with high fall risk) and a deprescribing tool were developed by a European expert group.

METHODS:

STOPPFall was created by two facilitators based on evidence from recent meta-analyses and national fall prevention guidelines in Europe. Twenty-four panellists chose their level of agreement on a Likert scale with the items in the STOPPFall in three Delphi panel rounds. A threshold of 70% was selected for consensus a priori. The panellists were asked whether some agents are more fall-risk-increasing than others within the same pharmacological class. In an additional questionnaire, panellists were asked in which cases deprescribing of FRIDs should be considered and how it should be performed.

RESULTS:

The panellists agreed on 14 medication classes to be included in the STOPPFall. They were mostly psychotropic medications. The panellists indicated 18 differences between pharmacological subclasses with regard to fall-risk-increasing properties. Practical deprescribing guidance was developed for STOPPFall medication classes.

CONCLUSION:

STOPPFall was created using an expert Delphi consensus process and combined with a practical deprescribing tool designed to optimise medication review. The effectiveness of these tools in falls prevention should be further evaluated in intervention studies.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acidentes por Quedas / Preparações Farmacêuticas Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Qualitative_research / Risk_factors_studies / Screening_studies Limite: Aged / Aged80 / Humans País/Região como assunto: Europa Idioma: En Revista: Age Ageing Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acidentes por Quedas / Preparações Farmacêuticas Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Qualitative_research / Risk_factors_studies / Screening_studies Limite: Aged / Aged80 / Humans País/Região como assunto: Europa Idioma: En Revista: Age Ageing Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda