Efficacy of sublingual immunotherapy tablets in dust mite and pollen allergy.

Bisyuk, Yuriy; DuBuske, Ilona; DuBuske, Lawrence M

Bisyuk, Yuriy; DuBuske, Ilona; DuBuske, Lawrence M.

Afiliação

Bisyuk Y; From the Department of Clinical Laboratory Immunology and Allergy, Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine.
DuBuske I; Immunology Research Institute of New England, Gardner, Massachusetts.
DuBuske LM; Immunology Research Institute of New England, Gardner, Massachusetts.

Allergy Asthma Proc ; 42(1): 36-42, 2021 01 01.

Article em En | MEDLINE | ID: mdl-33404387

RESUMO

The latest evidence on the mechanisms, efficacy, and safety of sublingual immunotherapy (SLIT) was reviewed. Interleukin (IL) 35 and IL-35-producing regulatory T cells were assessed as new biomarkers for SLIT responsiveness. A detailed analysis of clinical studies, including timothy grass pollen, 5-grass pollen, ragweed, and house-dust mite SLIT tablets, was provided, including a comparative analysis of efficacy and safety of SLIT versus subcutaneous immunotherapy.

Assuntos

Dessensibilização Imunológica/métodos; Hipersensibilidade/terapia; Administração Sublingual; Alérgenos/imunologia; Animais; Antígenos de Dermatophagoides/imunologia; Biomarcadores Farmacológicos; Humanos; Hipersensibilidade/imunologia; Injeções Subcutâneas; Pólen/imunologia; Pyroglyphidae; Resultado do Tratamento

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dessensibilização Imunológica / Hipersensibilidade Limite: Animals / Humans Idioma: En Revista: Allergy Asthma Proc Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Ucrânia

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