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Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity.
Hirosawa, Keiya; Fukami, Tatsuki; Tashiro, Kiyomichi; Sakai, Yoshiyuki; Kisui, Fumiya; Nakano, Masataka; Nakajima, Miki.
Afiliação
  • Hirosawa K; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan (K.H., T.F., K.T., Y.S., F.K., Ma.N., Mi.N.); and WPI Nano Life Science Institute, Kakuma-machi, Kanazawa, Japan (T.F., Ma.N., Mi.N.).
  • Fukami T; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan (K.H., T.F., K.T., Y.S., F.K., Ma.N., Mi.N.); and WPI Nano Life Science Institute, Kakuma-machi, Kanazawa, Japan (T.F., Ma.N., Mi.N.) tatsuki@p.kanazawa-u.ac.jp.
  • Tashiro K; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan (K.H., T.F., K.T., Y.S., F.K., Ma.N., Mi.N.); and WPI Nano Life Science Institute, Kakuma-machi, Kanazawa, Japan (T.F., Ma.N., Mi.N.).
  • Sakai Y; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan (K.H., T.F., K.T., Y.S., F.K., Ma.N., Mi.N.); and WPI Nano Life Science Institute, Kakuma-machi, Kanazawa, Japan (T.F., Ma.N., Mi.N.).
  • Kisui F; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan (K.H., T.F., K.T., Y.S., F.K., Ma.N., Mi.N.); and WPI Nano Life Science Institute, Kakuma-machi, Kanazawa, Japan (T.F., Ma.N., Mi.N.).
  • Nakano M; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan (K.H., T.F., K.T., Y.S., F.K., Ma.N., Mi.N.); and WPI Nano Life Science Institute, Kakuma-machi, Kanazawa, Japan (T.F., Ma.N., Mi.N.).
  • Nakajima M; Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan (K.H., T.F., K.T., Y.S., F.K., Ma.N., Mi.N.); and WPI Nano Life Science Institute, Kakuma-machi, Kanazawa, Japan (T.F., Ma.N., Mi.N.).
Drug Metab Dispos ; 49(4): 322-329, 2021 04.
Article em En | MEDLINE | ID: mdl-33446525
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Microssomos Hepáticos / Hidrolases de Éster Carboxílico / Dibenzazepinas Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Microssomos Hepáticos / Hidrolases de Éster Carboxílico / Dibenzazepinas Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article