Mobility performance impacts mortality risk in community-dwelling healthy older adults in Japan: a prospective observational study.
Aging Clin Exp Res
; 33(9): 2511-2517, 2021 Sep.
Article
em En
| MEDLINE
| ID: mdl-33496935
ABSTRACT
BACKGROUND:
The timed up and go (TUG) test assesses balance and mobility performance.AIM:
This study aims to investigate the association between TUG time and mortality in Japanese older persons and to clarify possible moderation effects on mortality and TUG time.METHODS:
In all, 874 participants who were ≥ 65 years of age completed the TUG test and had their anthropometric parameters and physical functions measured. We investigated the association between all-cause mortality and TUG using a Cox regression model that included confounders, and explored the time associated with mortality using a restricted cubic spline. We also performed subgroup analyses to explore whether age, sex, and body mass index (BMI) affected the relationship between TUG time and mortality.RESULTS:
The median age and mean follow-up period were 74 and 8.5 years, respectively. Median TUG time was 7.4 s and the prevalence of mortality was 25.7%. TUG time in one second was positively associated with an increased risk of total mortality [hazard ratio (HR) 1.054 (1.016-1.093); P = 0.005] in the Cox regression model. The positive association of mortality and TUG time was present when the TUG was over 10.5 s in the restricted cubic spline curve. Older age (75 years or older) moderated the relationship between TUG time and mortality [Pinteraction = 0.096].CONCLUSION:
This study demonstrates that TUG time is associated with all-cause mortality in Japanese older adults.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Avaliação Geriátrica
/
Vida Independente
Tipo de estudo:
Etiology_studies
/
Observational_studies
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Risk_factors_studies
Limite:
Aged
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Aged80
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Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Aging Clin Exp Res
Assunto da revista:
GERIATRIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Japão