Review of Intravenous Acetaminophen for Analgesia in the Postoperative Setting.
Am Surg
; 87(11): 1809-1822, 2021 Nov.
Article
em En
| MEDLINE
| ID: mdl-33522265
ABSTRACT
BACKGROUND:
Acetaminophen is a non-opioid analgesic commonly utilized for pain control after several types of surgical procedures.METHODS:
This scoping primary literature review provides recommendations for intravenous (IV) acetaminophen use based on type of surgery.RESULTS:
Intravenous acetaminophen has been widely studied for postoperative pain control and has been compared to other agents such as NSAIDs, opioids, oral/rectal acetaminophen, and placebo. Some of the procedures studied include abdominal, gynecologic, orthopedic, neurosurgical, cardiac, renal, and genitourinary surgeries. Results of these studies have been conflicting and largely have not shown consistent clinical benefit.CONCLUSION:
Overall, findings from this review did not support the notion that IV acetaminophen has significant efficacy for postoperative analgesia. Given the limited clinical benefit of IV acetaminophen, especially when compared to the oral or rectal formulations, use is generally not justifiable.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dor Pós-Operatória
/
Analgésicos não Narcóticos
/
Acetaminofen
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Guideline
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Am Surg
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos