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Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions.
Ginn, John; Jiang, Xiuju; Sun, Shan; Michino, Mayako; Huggins, David J; Mbambo, Zodwa; Jansen, Robert; Rhee, Kyu Y; Arango, Nancy; Lima, Christopher D; Liverton, Nigel; Imaeda, Toshihiro; Okamoto, Rei; Kuroita, Takanobu; Aso, Kazuyoshi; Stamford, Andrew; Foley, Michael; Meinke, Peter T; Nathan, Carl; Bryk, Ruslana.
Afiliação
  • Ginn J; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Sun S; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Michino M; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Huggins DJ; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Arango N; Structural Biology Program, Sloan Kettering Institute, New York, New York 10065, United States.
  • Lima CD; Structural Biology Program, Sloan Kettering Institute, New York, New York 10065, United States.
  • Liverton N; Howard Hughes Medical Institute, New York, New York 10065, United States.
  • Imaeda T; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Okamoto R; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Kuroita T; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Aso K; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Stamford A; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Foley M; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Meinke PT; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
  • Nathan C; Tri-Institutional Therapeutics Discovery Institute, New York, New York 10065, United States.
ACS Infect Dis ; 7(2): 435-444, 2021 02 12.
Article em En | MEDLINE | ID: mdl-33527832
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Limite: Animals / Humans Idioma: En Revista: ACS Infect Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Limite: Animals / Humans Idioma: En Revista: ACS Infect Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos