Medication utilization in children born preterm in the first two years of life.
J Perinatol
; 41(7): 1732-1738, 2021 07.
Article
em En
| MEDLINE
| ID: mdl-33547407
ABSTRACT
OBJECTIVE:
To compare medications dispensed during the first 2 years in children born preterm and full-term. STUDYDESIGN:
Retrospective analysis of claims data from a commercial national managed care plan 2008-2019. 329,855 beneficiaries were enrolled from birth through 2 years, of which 25,408 (7.7%) were preterm (<37 weeks). Filled prescription claims and paid amount over 2 years were identified.RESULTS:
In preterm children, the number of filled prescriptions was 1.4 times and cost was 3.8 times that of full-term children. Number and cost of medications were inversely related to gestational age. Differences peak at 4-9 months and resolve by 19 months after discharge. Palivizumab, ranitidine, albuterol, lansoprazole, budesonide, and prednisolone had the greatest differences in utilization.CONCLUSION:
Prescription medication utilization among preterm children under 2 years is driven by palivizumab, anti-reflux, and respiratory medications, despite little evidence regarding efficacy for many medications and concern for harm with certain classes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estudos Retrospectivos
Tipo de estudo:
Guideline
/
Observational_studies
Limite:
Child
/
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
J Perinatol
Assunto da revista:
PERINATOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos