How to Interpret Resting-State fMRI: Ask Your Participants.
J Neurosci
; 41(6): 1130-1141, 2021 02 10.
Article
em En
| MEDLINE
| ID: mdl-33568446
ABSTRACT
Resting-state fMRI (rsfMRI) reveals brain dynamics in a task-unconstrained environment as subjects let their minds wander freely. Consequently, resting subjects navigate a rich space of cognitive and perceptual states (i.e., ongoing experience). How this ongoing experience shapes rsfMRI summary metrics (e.g., functional connectivity) is unknown, yet likely to contribute uniquely to within- and between-subject differences. Here we argue that understanding the role of ongoing experience in rsfMRI requires access to standardized, temporally resolved, scientifically validated first-person descriptions of those experiences. We suggest best practices for obtaining those descriptions via introspective methods appropriately adapted for use in fMRI research. We conclude with a set of guidelines for fusing these two data types to answer pressing questions about the etiology of rsfMRI.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Descanso
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Pensamento
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Encéfalo
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Imageamento por Ressonância Magnética
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Guias de Prática Clínica como Assunto
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
J Neurosci
Ano de publicação:
2021
Tipo de documento:
Article