177Lu-PSMA-617 Therapy in Mice, with or without the Antioxidant &#945;1-Microglobulin (A1M), Including Kidney Damage Assessment Using 99mTc-MAG3 Imaging.

Kristiansson, Amanda; Örbom, Anders; Ahlstedt, Jonas; Karlsson, Helena; Zedan, Wahed; Gram, Magnus; Åkerström, Bo; Strand, Sven-Erik; Altai, Mohamed; Strand, Joanna; Vilhelmsson Timmermand, Oskar

¹⁷⁷Lu-PSMA-617 Therapy in Mice, with or without the Antioxidant α₁-Microglobulin (A1M), Including Kidney Damage Assessment Using ^99mTc-MAG3 Imaging.

Kristiansson, Amanda; Örbom, Anders; Ahlstedt, Jonas; Karlsson, Helena; Zedan, Wahed; Gram, Magnus; Åkerström, Bo; Strand, Sven-Erik; Altai, Mohamed; Strand, Joanna; Vilhelmsson Timmermand, Oskar.

Afiliação

Kristiansson A; Section for Infection Medicine, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.
Örbom A; Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, 221 84 Lund, Sweden.
Ahlstedt J; Division of Oncology, Department of Clinical Sciences Lund, Lund University, 221 00 Lund, Sweden.
Karlsson H; Lund University Bioimaging Center, Lund University, 221 84 Lund, Sweden.
Zedan W; Pediatrics, Department of Clinical Sciences Lund, Lund University, 221 84 Lund, Sweden.
Gram M; Division of Oncology, Department of Clinical Sciences Lund, Lund University, 221 00 Lund, Sweden.
Åkerström B; Pediatrics, Department of Clinical Sciences Lund, Lund University, 221 84 Lund, Sweden.
Strand SE; Section for Infection Medicine, Department of Clinical Sciences, Lund University, 221 84 Lund, Sweden.
Altai M; Division of Oncology, Department of Clinical Sciences Lund, Lund University, 221 00 Lund, Sweden.
Strand J; Division of Medical Radiation Physics, Department of Clinical Sciences Lund, Lund University, 221 00 Lund, Sweden.
Vilhelmsson Timmermand O; Division of Oncology, Department of Clinical Sciences Lund, Lund University, 221 00 Lund, Sweden.

Biomolecules ; 11(2)2021 02 10.

Article em En | MEDLINE | ID: mdl-33579037

Assuntos

alfa-Globulinas/metabolismo; Antioxidantes/química; Nefropatias/metabolismo; Lutécio/química; Radioisótopos/química; Tecnécio Tc 99m Mertiatida/química; Animais; Linhagem Celular Tumoral; Dipeptídeos; Compostos Heterocíclicos com 1 Anel; Humanos; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Antígeno Prostático Específico; Radiometria; Compostos Radiofarmacêuticos; Tomografia Computadorizada de Emissão de Fóton Único

Palavras-chave

[177Lu]Lu-PSMA-617; [99mTc]Tc-MAG3 imaging; dosimetry; kidney damage; mouse model; prostate cancer; radioligand therapy; α1-microglobulin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radioisótopos / Alfa-Globulinas / Tecnécio Tc 99m Mertiatida / Nefropatias / Lutécio / Antioxidantes Limite: Animals / Humans / Male Idioma: En Revista: Biomolecules Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suécia

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