Molybdenum-containing polypyrrole self-supporting hollow flexible electrode for hydrogen peroxide detection in living cells.

ABSTRACT

A flexible electrode based on polypyrrole-supported free-standing molybdenum oxide-molybdenum disulfide/polypyrrole nanostructure (MoO3-MoS2/PPy) was synthesized. The petal-like MoO3-MoS2 sheets grown on PPy were prepared step by step through simple electrodeposition and hydrothermal methods. The corresponding surface morphological and structural characterizations were characterized by field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The results showed that the prepared petal MoO3-MoS2 hybrid nanomaterials were uniformly distributed on the PPy skeleton and exhibited a three-dimensional porous network structure. The flexible electrode was used for non-enzymatic detection of hydrogen peroxide (H2O2), and the developed MoO3-MoS2/PPy nanomaterials exhibited high electrochemical sensing performance in the range of 0.3-150 µM, with the detection limit of 0.18 µM (S/N = 3). The excellent detection properties enabled the MoO3-MoS2/PPy flexible electrode to detect H2O2 released by living cells. The resulting MoO3-MoS2/PPy flexible electrode also has the advantages of customizable shape and adjustability, which provides a potential platform for constructing clinically diagnosed in vivo portable instruments and real-time environmental monitoring.