Effectiveness of salvage intratympanic dexamethasone treatment for refractory sudden sensorineural hearing loss classified by audiogram patterns.
Acta Otolaryngol
; 141(5): 449-453, 2021 May.
Article
em En
| MEDLINE
| ID: mdl-33645435
ABSTRACT
BACKGROUND:
Intratympanic dexamethasone is commonly conducted to treat refractory sudden sensorineural hearing loss (RSSNHL). However, no consensus has been reached on its effectiveness.OBJECTIVES:
The study aimed to evaluate the effectiveness of otoendoscope-assisted salvage intratympanic dexamethasone treatment (IDT) on RSSNHL with different audiogram patterns after failure of initial therapy. MATERIAL ANDMETHODS:
A total of 108 patients with unilateral RSSNHL were classified into 4 groups according to audiogram patterns. Hearing results were evaluated by pure-tone audiometry (PTA), which was performed at baseline and one month after otoendoscope-assisted salvage IDT. The effectiveness of otoendoscope-assisted salvage IDT was assessed in each group.RESULTS:
The efficiency in low-frequency, high-frequency, flat, and deaf group was 48%, 24.1%, 46.2%, 17.9%, respectively. The efficacy did not differ between the high-frequency and deaf group. Notably, the efficacy in the low-frequency and flat group was significantly higher than that in the deaf group.CONCLUSIONS:
Otoendoscope-assisted salvage IDT is a safe and effective treatment for RSSNHL. This treatment provided better results for patients with low-frequency damaged and flat curve audiogram than patients with other audiogram patterns.SIGNIFICANCE:
Audiogram patterns should be considered in the clinical management of patients with RSSHNL prior to salvage IDT.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Dexametasona
/
Perda Auditiva Neurossensorial
/
Anti-Inflamatórios
Tipo de estudo:
Diagnostic_studies
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Observational_studies
Limite:
Adult
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Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Acta Otolaryngol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
China