Gene-based analysis of bi-variate survival traits via functional regressions with applications to eye diseases.

Zhang, Bingsong; Chiu, Chi-Yang; Yuan, Fang; Sang, Tian; Cook, Richard J; Wilson, Alexander F; Bailey-Wilson, Joan E; Chew, Emily Y; Xiong, Momiao; Fan, Ruzong

Zhang, Bingsong; Chiu, Chi-Yang; Yuan, Fang; Sang, Tian; Cook, Richard J; Wilson, Alexander F; Bailey-Wilson, Joan E; Chew, Emily Y; Xiong, Momiao; Fan, Ruzong.

Afiliação

Zhang B; Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, District of Columbia, USA.
Chiu CY; Division of Biostatistics, Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Yuan F; Computational and Statistical Genomics Branch, National Human Genome, Research Institute, National Institutes of Health (NIH), Baltimore, Maryland, USA.
Sang T; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Kunming Medical University, Kunming, People's Republic of China.
Cook RJ; Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, District of Columbia, USA.
Wilson AF; School of Mathematics, Physics and Statistics, Shanghai University of Engineering Science, Shanghai, China.
Bailey-Wilson JE; Department of Statistics and Actuarial Science, Waterloo, Ontario, Canada.
Chew EY; Computational and Statistical Genomics Branch, National Human Genome, Research Institute, National Institutes of Health (NIH), Baltimore, Maryland, USA.
Xiong M; Computational and Statistical Genomics Branch, National Human Genome, Research Institute, National Institutes of Health (NIH), Baltimore, Maryland, USA.
Fan R; Division of Epidemiology and Clinical Applications, National Eye Institute, NIH, Bethesda, Maryland, USA.

Genet Epidemiol ; 45(5): 455-470, 2021 07.

Article em En | MEDLINE | ID: mdl-33645812

Assuntos

Oftalmopatias; Variação Genética; Oftalmopatias/genética; Estudos de Associação Genética; Humanos; Modelos Genéticos; Fenótipo

Palavras-chave

association study; common variants; complex diseases; functional data analysis; mixed effect Cox models; rare variants

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Variação Genética / Oftalmopatias Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Genet Epidemiol Assunto da revista: EPIDEMIOLOGIA / GENETICA MEDICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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