Cembranoids from Octocoral Lobophytum crassum (von Marenzeller, 1886).
Mar Drugs
; 19(3)2021 Feb 27.
Article
em En
| MEDLINE
| ID: mdl-33673526
ABSTRACT
Two cembranoids, including a new compound, lobocrassin I (1), as well as a known analogue, lobohedleolide (2), were obtained by solvent extraction from octocoral Lobophytum crassum. This study employed a spectroscopic approach to establish the structures of these two cembranoids, and utilized single-crystal X-ray diffraction analysis to determine their absolute configurations. The results of biological activity assays demonstrated that cembranoid 2 exhibited bioactivity against the protein expressions of inducible nitric oxide synthase (iNOS) lipopolysaccharide (LPS)-treated RAW 264.7 mouse macrophage cells.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antozoários
/
Diterpenos
/
Anti-Inflamatórios
Limite:
Animals
Idioma:
En
Revista:
Mar Drugs
Assunto da revista:
BIOLOGIA
/
FARMACOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Taiwan