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A retrospective study on the usefulness of the JJ risk engine for predicting the incidence rate of coronary heart disease in type 2 diabetes patients.
Yamashita, Yasunari; Kitajima, Rina; Matsubara, Kiyoshi; Inoue, Gaku; Matsubara, Hajime.
Afiliação
  • Yamashita Y; Division of Clinical Pharmacy (Laboratory of Pharmacy Practice and Science III), and Research and Education Center for Clinical Pharmacy, School of Pharmacy, Kitasato University, 9-1, Shirokane 5-Chome, Minato-ku, Tokyo, 108-8641, Japan. dp18205@st.kitasato-u.ac.jp.
  • Kitajima R; Division of Clinical Pharmacy (Laboratory of Pharmacy Practice and Science III), and Research and Education Center for Clinical Pharmacy, School of Pharmacy, Kitasato University, 9-1, Shirokane 5-Chome, Minato-ku, Tokyo, 108-8641, Japan.
  • Matsubara K; Division of Clinical Pharmacy (Laboratory of Pharmacy Practice and Science III), and Research and Education Center for Clinical Pharmacy, School of Pharmacy, Kitasato University, 9-1, Shirokane 5-Chome, Minato-ku, Tokyo, 108-8641, Japan.
  • Inoue G; AdvanceSoft Corporation, 4-3, Kandasurugadai, Chiyoda-ku, Tokyo, 101-0062, Japan.
  • Matsubara H; Division of Clinical Pharmacy (Laboratory of Pharmacy Practice and Science III), and Research and Education Center for Clinical Pharmacy, School of Pharmacy, Kitasato University, 9-1, Shirokane 5-Chome, Minato-ku, Tokyo, 108-8641, Japan.
BMC Res Notes ; 14(1): 92, 2021 Mar 09.
Article em En | MEDLINE | ID: mdl-33750456
ABSTRACT

OBJECTIVE:

In 2018, we conducted a retrospective survey using the medical records of 484 patients with type 2 diabetes. The observed value of coronary heart disease (CHD) incidence after 5 years and the predicted value by the JJ risk engine as of 2013 were compared and verified using the discrimination and calibration values.

RESULTS:

Among the total cases analyzed, the C-statistic was 0.588, and the calibration was p < 0.05; thus, the JJ risk engine could not correctly predict the risk of CHD. However, in the group expected to have a low frequency of hypoglycemia, the C-statistic was 0.646; the predictability of the JJ risk engine was relatively accurate. Therefore, it is difficult to accurately predict the complication rate of patients using the JJ risk engine based on the diabetes treatment policy after the Kumamoto Declaration 2013. The JJ risk engine has several input items (variables), and it is difficult to satisfy them all unless the environment is well-equipped with testing facilities, such as a university hospital. Therefore, it is necessary to create a new risk engine that requires fewer input items than the JJ risk engine and is applicable to several patients.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença das Coronárias / Diabetes Mellitus Tipo 2 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Res Notes Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença das Coronárias / Diabetes Mellitus Tipo 2 Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Res Notes Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão