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Anti-fibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis.
Li, Guorong; Lee, Chanyoung; Read, A Thomas; Wang, Ke; Ha, Jungmin; Kuhn, Megan; Navarro, Iris; Cui, Jenny; Young, Katherine; Gorijavolu, Rahul; Sulchek, Todd; Kopczynski, Casey; Farsiu, Sina; Samples, John; Challa, Pratap; Ethier, C Ross; Stamer, W Daniel.
Afiliação
  • Li G; Department of Ophthalmology, Duke University, Durham, United States.
  • Lee C; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, United States.
  • Read AT; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, United States.
  • Wang K; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, United States.
  • Ha J; Department of Mechanical Engineering, Georgia Institute of Technology, Atlanta, United States.
  • Kuhn M; Department of Ophthalmology, Duke University, Durham, United States.
  • Navarro I; Department of Ophthalmology, Duke University, Durham, United States.
  • Cui J; Department of Ophthalmology, Duke University, Durham, United States.
  • Young K; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, United States.
  • Gorijavolu R; Department of Ophthalmology, Duke University, Durham, United States.
  • Sulchek T; Department of Mechanical Engineering, Georgia Institute of Technology, Atlanta, United States.
  • Kopczynski C; Aerie Pharmaceuticals, Inc, Durham, United States.
  • Farsiu S; Department of Ophthalmology, Duke University, Durham, United States.
  • Samples J; Department of Biomedical Engineering, Duke University, Durham, United States.
  • Challa P; Washington State University Floyd Elson School of Medicine, Spokane, United States.
  • Ethier CR; Department of Ophthalmology, Duke University, Durham, United States.
  • Stamer WD; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, United States.
Elife ; 102021 03 30.
Article em En | MEDLINE | ID: mdl-33783352
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzoatos / Hipertensão Ocular / Beta-Alanina / Quinases Associadas a rho / Pressão Intraocular / Anti-Hipertensivos Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged / Newborn Idioma: En Revista: Elife Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzoatos / Hipertensão Ocular / Beta-Alanina / Quinases Associadas a rho / Pressão Intraocular / Anti-Hipertensivos Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged / Newborn Idioma: En Revista: Elife Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos