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Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma-rationale for targeting ARID1A deficiency.
Dong, Xiaochuan; Song, Shumei; Li, Yuan; Fan, Yibo; Wang, Lulu; Wang, Ruiping; Huo, Longfei; Scott, Ailing; Xu, Yan; Pizzi, Melissa Pool; Ma, Lang; Wang, Ying; Jin, Jiangkang; Zhao, Wei; Yao, Xiaodan; Johnson, Randy L; Wang, Linghua; Wang, Zhenning; Peng, Guang; Ajani, Jaffer A.
Afiliação
  • Dong X; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Song S; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Li Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA ssong@mdanderson.org jajani@mdanderson.org.
  • Fan Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Wang L; Department of Surgical Oncology and General Surgery, The First Hospital of China Medical University, Shenyang, P.R.China.
  • Wang R; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Huo L; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Scott A; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Xu Y; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Pizzi MP; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Ma L; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Wang Y; Department of Surgical Oncology and General Surgery, The First Hospital of China Medical University, Shenyang, P.R.China.
  • Jin J; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Zhao W; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Yao X; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Johnson RL; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Wang L; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Wang Z; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Peng G; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
  • Ajani JA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Gut ; 71(3): 467-478, 2022 03.
Article em En | MEDLINE | ID: mdl-33785559
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Fatores de Transcrição / Adenocarcinoma / Transdução de Sinais / Proteínas de Ligação a DNA / Fatores de Transcrição SOX9 / Serina-Treonina Quinases TOR Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Gut Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Fatores de Transcrição / Adenocarcinoma / Transdução de Sinais / Proteínas de Ligação a DNA / Fatores de Transcrição SOX9 / Serina-Treonina Quinases TOR Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Gut Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos