Fenamates as Potential Therapeutics for Neurodegenerative Disorders.
Cells
; 10(3)2021 03 22.
Article
em En
| MEDLINE
| ID: mdl-33809987
ABSTRACT
Neurodegenerative disorders are desperately lacking treatment options. It is imperative that drug repurposing be considered in the fight against neurodegenerative diseases. Fenamates have been studied for efficacy in treating several neurodegenerative diseases. The purpose of this review is to comprehensively present the past and current research on fenamates in the context of neurodegenerative diseases with a special emphasis on tolfenamic acid and Alzheimer's disease. Furthermore, this review discusses the major molecular pathways modulated by fenamates.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Anti-Inflamatórios não Esteroides
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Fármacos Neuroprotetores
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Doenças Neurodegenerativas
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Fenamatos
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Degeneração Neural
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Neurônios
Limite:
Animals
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Humans
Idioma:
En
Revista:
Cells
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos