Reduction in miR-219 expression underlies cellular pathogenesis of oligodendrocytes in a mouse model of Krabbe disease.

Inamura, Naoko; Go, Shinji; Watanabe, Takashi; Takase, Hiroshi; Takakura, Nobuyuki; Nakayama, Atsuo; Takebayashi, Hirohide; Matsuda, Junko; Enokido, Yasushi

Inamura, Naoko; Go, Shinji; Watanabe, Takashi; Takase, Hiroshi; Takakura, Nobuyuki; Nakayama, Atsuo; Takebayashi, Hirohide; Matsuda, Junko; Enokido, Yasushi.

Afiliação

Inamura N; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Japan.
Go S; Department of Pathophysiology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Watanabe T; Department of Pathophysiology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
Takase H; Core Laboratory, Nagoya City University Graduate School of Medical Science, Nagoya, Japan.
Takakura N; Department of Signal Transduction, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Nakayama A; Department of Cellular Pathology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Japan.
Takebayashi H; Department of Neurobiochemistry, Nagoya University School of Medicine, Nagoya, Japan.
Matsuda J; Division of Neurobiology and Anatomy, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Enokido Y; Department of Pathophysiology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.

Brain Pathol ; 31(5): e12951, 2021 09.

Article em En | MEDLINE | ID: mdl-33822434

Assuntos

Leucodistrofia de Células Globoides/patologia; MicroRNAs/genética; Oligodendroglia/patologia; Psicosina/metabolismo; Animais; Apoptose/genética; Apoptose/fisiologia; Modelos Animais de Doenças; Leucodistrofia de Células Globoides/genética; Leucodistrofia de Células Globoides/metabolismo; Camundongos Transgênicos; Oligodendroglia/metabolismo

Palavras-chave

Krabbe disease; demyelination; globoid cell leukodystrophy; lysosomal storage disease; microRNA; oligodendrocyte

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psicosina / Oligodendroglia / MicroRNAs / Leucodistrofia de Células Globoides Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Brain Pathol Assunto da revista: CEREBRO / PATOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google