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Development of a method for generating SNP interaction-aware polygenic risk scores for radiotherapy toxicity.
Franco, Nicola Rares; Massi, Michela Carlotta; Ieva, Francesca; Manzoni, Andrea; Paganoni, Anna Maria; Zunino, Paolo; Veldeman, Liv; Ost, Piet; Fonteyne, Valérie; Talbot, Christopher J; Rattay, Tim; Webb, Adam; Johnson, Kerstie; Lambrecht, Maarten; Haustermans, Karin; De Meerleer, Gert; de Ruysscher, Dirk; Vanneste, Ben; Van Limbergen, Evert; Choudhury, Ananya; Elliott, Rebecca M; Sperk, Elena; Veldwijk, Marlon R; Herskind, Carsten; Avuzzi, Barbara; Noris Chiorda, Barbara; Valdagni, Riccardo; Azria, David; Farcy-Jacquet, Marie-Pierre; Brengues, Muriel; Rosenstein, Barry S; Stock, Richard G; Vega, Ana; Aguado-Barrera, Miguel E; Sosa-Fajardo, Paloma; Dunning, Alison M; Fachal, Laura; Kerns, Sarah L; Payne, Debbie; Chang-Claude, Jenny; Seibold, Petra; West, Catharine M L; Rancati, Tiziana.
Afiliação
  • Franco NR; MOX, Department of Mathematics, Politecnico di Milano, Italy. Electronic address: nicolarares.franco@polimi.it.
  • Massi MC; MOX, Department of Mathematics, Politecnico di Milano, Italy; CADS-Center for Analysis, Decisions and Society, Human Technopole, Milan, Italy. Electronic address: michelacarlotta.massi@polimi.it.
  • Ieva F; MOX, Department of Mathematics, Politecnico di Milano, Italy; CADS-Center for Analysis, Decisions and Society, Human Technopole, Milan, Italy; CHRP-National Center for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy. Electronic address: francesca.ieva@polimi.
  • Manzoni A; MOX, Department of Mathematics, Politecnico di Milano, Italy. Electronic address: andrea1.manzoni@polimi.it.
  • Paganoni AM; MOX, Department of Mathematics, Politecnico di Milano, Italy; CADS-Center for Analysis, Decisions and Society, Human Technopole, Milan, Italy; CHRP-National Center for Healthcare Research and Pharmacoepidemiology, University of Milano-Bicocca, Milan, Italy. Electronic address: anna.paganoni@polimi.i
  • Zunino P; MOX, Department of Mathematics, Politecnico di Milano, Italy. Electronic address: paolo.zunino@polimi.it.
  • Veldeman L; Department of Human Structure and Repair, Ghent University, Belgium; Department of Radiation Oncology, Ghent University Hospital, Belgium. Electronic address: liv.veldeman@ugent.be.
  • Ost P; Department of Human Structure and Repair, Ghent University, Belgium; Department of Radiation Oncology, Ghent University Hospital, Belgium. Electronic address: piet.ost@ugent.be.
  • Fonteyne V; Department of Human Structure and Repair, Ghent University, Belgium; Department of Radiation Oncology, Ghent University Hospital, Belgium. Electronic address: valerie.fonteyne@uzgent.be.
  • Talbot CJ; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, United Kingdom. Electronic address: cjt14@leicester.ac.uk.
  • Rattay T; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, United Kingdom. Electronic address: tr104@leicester.ac.uk.
  • Webb A; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, United Kingdom. Electronic address: ajw51@leicester.ac.uk.
  • Johnson K; Leicester Cancer Research Centre, Department of Genetics and Genome Biology, University of Leicester, United Kingdom. Electronic address: kj91@leicester.ac.uk.
  • Lambrecht M; Department of Radiation Oncology, University Hospitals Leuven, Belgium. Electronic address: maarten.lambrecht@uzleuven.be.
  • Haustermans K; Department of Radiation Oncology, University Hospitals Leuven, Belgium. Electronic address: karin.haustermans@uzleuven.be.
  • De Meerleer G; Department of Radiation Oncology, University Hospitals Leuven, Belgium. Electronic address: gert.demeerleer@uzleuven.be.
  • de Ruysscher D; Maastricht University Medical Center, the Netherlands; Department of Radiation Oncology (Maastro), GROW Institute for Oncology and Developmental Biology, Maastricht, the Netherlands. Electronic address: dirk.deruysscher@maastro.nl.
  • Vanneste B; Department of Radiation Oncology (Maastro), GROW Institute for Oncology and Developmental Biology, Maastricht, the Netherlands. Electronic address: ben.vanneste@maastro.nl.
  • Van Limbergen E; Maastricht University Medical Center, the Netherlands; Department of Radiation Oncology (Maastro), GROW Institute for Oncology and Developmental Biology, Maastricht, the Netherlands. Electronic address: evert.vanlimbergen@maastro.nl.
  • Choudhury A; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, UK. Electronic address: ananya.choudhury@nhs.net.
  • Elliott RM; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, UK. Electronic address: rebecca.m.elliott@manchester.ac.uk.
  • Sperk E; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany. Electronic address: Elena.sperk@umm.de.
  • Veldwijk MR; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany. Electronic address: marlon.veldwijk@medma.uni-heidelberg.de.
  • Herskind C; Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany. Electronic address: Carsten.herskind@medma.uni-heidelberg.de.
  • Avuzzi B; Department of Radiation Oncology 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: barbara.avuzzi@istitutotumori.mi.it.
  • Noris Chiorda B; Department of Radiation Oncology 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: Barbara.Noris@istitutotumori.mi.it.
  • Valdagni R; Department of Radiation Oncology 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology and Haemato-Oncology, Università degli Studi di Milano, Milan, Italy; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: ri
  • Azria D; Department of Radiation Oncology, University Federation of Radiation Oncology, Montpellier Cancer Institute, Univ Montpellier MUSE, France. Electronic address: David.Azria@icm.unicancer.fr.
  • Farcy-Jacquet MP; Department of Radiation Oncology, University Federation of Radiation Oncology, Institut de Cancérologie du Gard, Nimes, France. Electronic address: marie.pierre.farcy.jacquet@chu-nimes.fr.
  • Brengues M; Department of Radiation Oncology, University Federation of Radiation Oncology, Montpellier Cancer Institute, Univ Montpellier MUSE, France. Electronic address: muriel.brengues@icm.unicancer.fr.
  • Rosenstein BS; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, USA. Electronic address: Barry.Rosenstein@mssm.edu.
  • Stock RG; Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, USA. Electronic address: richard.stock@mssm.edu.
  • Vega A; Grupo de Medicina Xenómica (USC), Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Biomedical Network on Rare Diseases (CIBERER), Spain. Electronic address: ana.vega@usc.es.
  • Aguado-Barrera ME; Grupo de Medicina Xenómica (USC), Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain. Electronic address: miguelelias.aguado@usc.es.
  • Sosa-Fajardo P; Grupo de Medicina Xenómica (USC), Fundación Pública Galega de Medicina Xenómica, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Spain; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain. Ele
  • Dunning AM; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Labs, UK. Electronic address: amd24@medschl.cam.ac.uk.
  • Fachal L; Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Labs, UK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. Electronic address: lf370@medschl.cam.ac.uk.
  • Kerns SL; Departments of Radiation Oncology and Surgery, University of Rochester Medical Center, Rochester, USA. Electronic address: Sarah_Kerns@URMC.Rochester.edu.
  • Payne D; Centre for Integrated Genomic Medical Research (CIGMR), University of Manchester, UK. Electronic address: Debbie.Payne@manchester.ac.uk.
  • Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Germany. Electronic address: j.chang-claude@dkfz-heidelberg.de.
  • Seibold P; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: p.seibold@Dkfz-Heidelberg.de.
  • West CML; Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, UK. Electronic address: Catharine.West@manchester.ac.uk.
  • Rancati T; Prostate Cancer Program, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address: Tiziana.rancati@istitutotumori.mi.it.
Radiother Oncol ; 159: 241-248, 2021 06.
Article em En | MEDLINE | ID: mdl-33838170
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Lesões por Radiação Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Radiother Oncol Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Lesões por Radiação Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Radiother Oncol Ano de publicação: 2021 Tipo de documento: Article