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Novel Preclinical Patient-Derived Lung Cancer Models Reveal Inhibition of HER3 and MTOR Signaling as Therapeutic Strategies for NRG1 Fusion-Positive Cancers.
Odintsov, Igor; Mattar, Marissa S; Lui, Allan J W; Offin, Michael; Kurzatkowski, Christopher; Delasos, Lukas; Khodos, Inna; Asher, Marina; Daly, Robert M; Rekhtman, Natasha; de Stanchina, Elisa; Ganji, Gopinath; Ladanyi, Marc; Somwar, Romel.
Afiliação
  • Odintsov I; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Mattar MS; Anti-Tumor Assessment Core Facility, Department of Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Lui AJW; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Offin M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Kurzatkowski C; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Delasos L; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Khodos I; Anti-Tumor Assessment Core Facility, Department of Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Asher M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Daly RM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Rekhtman N; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • de Stanchina E; Anti-Tumor Assessment Core Facility, Department of Pharmacology, Memorial Sloan Kettering Cancer Center, New York, New York.
  • Ganji G; Research and Development, GlaxoSmithKline, Collegeville, Pennsylvania.
  • Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: ladanyim@mskcc.org.
  • Somwar R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.
J Thorac Oncol ; 16(7): 1149-1165, 2021 07.
Article em En | MEDLINE | ID: mdl-33839363

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteômica / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Thorac Oncol Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteômica / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Thorac Oncol Ano de publicação: 2021 Tipo de documento: Article