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Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response.
Xue, Peng; Hu, Xiangxiang; Chang, Emily; Wang, Lufei; Chen, Minghui; Wu, Tai-Hsien; Lee, Dong-Joon; Foster, Brian L; Tseng, Henry C; Ko, Ching-Chang.
Afiliação
  • Xue P; Oral and Craniofacial Health Science Institute, School of Dentistry, UNC at Chapel Hill, North Carolina, NC, USA.
  • Hu X; Oral and Craniofacial Health Science Institute, School of Dentistry, UNC at Chapel Hill, North Carolina, NC, USA.
  • Chang E; Division of Orthodontics, The Ohio State University College of Dentistry, Columbus, OH, 43210, USA.
  • Wang L; Duke Eye Center and Department of Ophthalmology, Duke University Medical Center, Durham, NC, 27710, USA.
  • Chen M; Oral and Craniofacial Health Science Institute, School of Dentistry, UNC at Chapel Hill, North Carolina, NC, USA.
  • Wu TH; Division of Orthodontics, The Ohio State University College of Dentistry, Columbus, OH, 43210, USA.
  • Lee DJ; Oral and Craniofacial Health Science Institute, School of Dentistry, UNC at Chapel Hill, North Carolina, NC, USA.
  • Foster BL; Division of Orthodontics, The Ohio State University College of Dentistry, Columbus, OH, 43210, USA.
  • Tseng HC; Oral and Craniofacial Health Science Institute, School of Dentistry, UNC at Chapel Hill, North Carolina, NC, USA.
  • Ko CC; Division of Biosciences, The Ohio State University College of Dentistry, Columbus, OH, 43210, USA.
Exp Mol Med ; 53(4): 667-680, 2021 04.
Article em En | MEDLINE | ID: mdl-33864025

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Osteogênese / Proteínas de Membrana Transportadoras / Diferenciação Celular / Proteínas de Ciclo Celular / Fator 2 Relacionado a NF-E2 / Antioxidantes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Exp Mol Med Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoclastos / Osteogênese / Proteínas de Membrana Transportadoras / Diferenciação Celular / Proteínas de Ciclo Celular / Fator 2 Relacionado a NF-E2 / Antioxidantes Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Exp Mol Med Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos