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Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer.
Gupta, Vijayalaxmi G; Hirst, Jeff; Petersen, Shariska; Roby, Katherine F; Kusch, Meghan; Zhou, Helen; Clive, Makena L; Jewell, Andrea; Pathak, Harsh B; Godwin, Andrew K; Wilson, Andrew J; Crispens, Marta A; Cybulla, Emily; Vindigni, Alessandro; Fuh, Katherine C; Khabele, Dineo.
Afiliação
  • Gupta VG; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Hirst J; Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Petersen S; Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Roby KF; Department of Anatomy and Cell Biology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Kusch M; Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Zhou H; Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Clive ML; Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Jewell A; Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Pathak HB; Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Godwin AK; Department of Pathology and Laboratory Medicine, The University of Kansas Medical Center, Kansas City, KS 66160, USA; Univeristy of Kansas Cancer Center, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Wilson AJ; Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN 37235, USA.
  • Crispens MA; Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN 37235, USA.
  • Cybulla E; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.
  • Vindigni A; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Fuh KC; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Khabele D; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: khabeled@wustl.edu.
Gynecol Oncol ; 162(1): 163-172, 2021 07.
Article em En | MEDLINE | ID: mdl-33867143
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Ftalazinas / Piperazinas / Piridinas / Benzamidas / Protocolos de Quimioterapia Combinada Antineoplásica / Inibidores de Histona Desacetilases / Inibidores de Poli(ADP-Ribose) Polimerases / Carcinoma Epitelial do Ovário Tipo de estudo: Clinical_trials Limite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Ftalazinas / Piperazinas / Piridinas / Benzamidas / Protocolos de Quimioterapia Combinada Antineoplásica / Inibidores de Histona Desacetilases / Inibidores de Poli(ADP-Ribose) Polimerases / Carcinoma Epitelial do Ovário Tipo de estudo: Clinical_trials Limite: Animals / Female / Humans Idioma: En Revista: Gynecol Oncol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos